RGD Reference Report - The expression of SCDGF/PDGF-C/fallotein and SCDGF-B/PDGF-D in the rat central nervous system. - Rat Genome Database

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The expression of SCDGF/PDGF-C/fallotein and SCDGF-B/PDGF-D in the rat central nervous system.

Authors: Hamada, T  Ui-Tei, K  Imaki, J  Takahashi, F  Onodera, H  Mishima, T  Miyata, Y 
Citation: Hamada T, etal., Mech Dev 2002 Mar;112(1-2):161-4.
RGD ID: 633568
Pubmed: PMID:11850188   (View Abstract at PubMed)

We examined the expression patterns of the two homologous genes, spinal cord-derived growth factor (SCDGF)/platelet-derived growth factor (PDGF)-C/fallotein and SCDGF-B/PDGF-D in the rat central nervous system. In the spinal cord, SCDGF/PDGF-C/fallotein was expressed in the floor plate at embryonic day (E) 11 and also in the ventricular zone at E16 but not in adult. However, SCDGF-B/PDGF-D was prominently expressed in the adult motoneurons, although faint expression was observed in the ventral ventricular zone at E16. Also in the brain, the expression of SCDGF/PDGF-C/fallotein was more remarkable at E16 than at adult. It was highly expressed in the cortex, pontine area and choroid plexus at E16. Contrary to SCDGF/PDGF-C/fallotein, SCDGF-B/PDGF-D expression was notable in several nuclei at adult.

Objects referenced in this article
Gene Pdgfc platelet derived growth factor C Rattus norvegicus
Gene Pdgfd platelet derived growth factor D Rattus norvegicus

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