RGD Reference Report - Cloning and identification of testis-specific transcription elongation factor S-II. - Rat Genome Database

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Cloning and identification of testis-specific transcription elongation factor S-II.

Authors: Xu, Q  Nakanishi, T  Sekimizu, K  Natori, S 
Citation: Xu Q, etal., J Biol Chem 1994 Jan 28;269(4):3100-3.
RGD ID: 61763
Pubmed: PMID:8300645   (View Abstract at PubMed)

A new S-II cDNA clone was isolated from a rat testis library. This cDNA contained an open reading frame encoding 299 amino acid residues. The deduced amino- and carboxyl-terminal regions were very similar with those of Ehrlich cell S-II, which we reported previously, but the sequence of the intervening 46 amino acid residues was unique. This new S-II was expressed in the testis but not in the other rat tissues examined, suggesting that it was a testis-specific S-II. Recombinant testis-specific S-II produced in Escherichia coli was shown to stimulate RNA polymerase II.

Gene Ontology Annotations    Click to see Annotation Detail View

Biological Process
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
positive regulation of transcription by RNA polymerase II  IDA 61763 RGD 

Objects Annotated

Genes (Rattus norvegicus)
Tcea2  (transcription elongation factor A2)


Additional Information