RGD Reference Report - Nuclear receptor binding factor-2 (NRBF-2), a possible gene activator protein interacting with nuclear hormone receptors. - Rat Genome Database

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Nuclear receptor binding factor-2 (NRBF-2), a possible gene activator protein interacting with nuclear hormone receptors.

Authors: Yasumo, H  Masuda, N  Furusawa, T  Tsukamoto, T  Sadano, H  Osumi, T 
Citation: Yasumo H, etal., Biochim Biophys Acta 2000 Jan 31;1490(1-2):189-97.
RGD ID: 61677
Pubmed: PMID:10786636   (View Abstract at PubMed)

A protein named nuclear receptor binding factor-2 (NRBF-2) was identified by yeast two-hybrid screening, as an interaction partner of peroxisome proliferator-activated receptor alpha as well as several other nuclear receptors. NRBF-2 exhibited a gene activation function, when tethered to a heterologous DNA binding domain, in both mammalian cells and yeast.

Gene Ontology Annotations    Click to see Annotation Detail View

Biological Process
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
positive regulation of DNA-templated transcription  IDA 61677 RGD 

Molecular Function
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
nuclear receptor binding  IDA 61677 RGD 

Objects Annotated

Genes (Rattus norvegicus)
Nrbf2  (nuclear receptor binding factor 2)

Objects referenced in this article
Gene NRBF2 nuclear receptor binding factor 2 Homo sapiens

Additional Information