RGD Reference Report - Development of adenylate kinase isoenzymes in rat liver. - Rat Genome Database

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Development of adenylate kinase isoenzymes in rat liver.

Authors: Filler, R  Criss, WE 
Citation: Filler R and Criss WE, Biochem J. 1971 May;122(4):553-5.
RGD ID: 5490208
Pubmed: (View Article at PubMed) PMID:5123889

Total adenylate kinase activity was determined in developing rat liver. The activity was 18 units/g wet weight of tissue in foetal liver; this increased to 41 units/g immediately after birth and continued increasing until adult activities of 150 units/g were reached after two weeks. The adenylate kinase activity was separated into four isoenzymes. Only isoenzymes II and III were observed in foetal rat liver. Isoenzyme II activity was 2 units/g in the foetal liver and increased to 25 units/g in adult liver. Adenylate kinase III activity was 20 units/g in the foetal liver and increased to 118 units/g in adult liver. The possible role that adenylate kinase might have in regulating the energy flow in the developing liver cell is discussed.

Annotation

Gene Ontology Annotations    

Biological Process

Objects Annotated

Genes (Rattus norvegicus)
Ak2  (adenylate kinase 2)
Ak3  (adenylate kinase 3)


Additional Information