RGD Reference Report - The JNK signal transduction pathway. - Rat Genome Database

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The JNK signal transduction pathway.

Authors: Weston, CR  Davis, RJ 
Citation: Weston CR and Davis RJ, Curr Opin Cell Biol. 2007 Apr;19(2):142-9. Epub 2007 Feb 15.
RGD ID: 5129911
Pubmed: PMID:17303404   (View Abstract at PubMed)
DOI: DOI:10.1016/j.ceb.2007.02.001   (Journal Full-text)

The c-Jun NH(2)-terminal kinases (JNKs) are an evolutionarily conserved sub-group of mitogen-activated protein (MAP) kinases. Recent studies have improved our understanding of the physiological function of the JNK pathway. Roles of novel molecules that participate in the JNK pathway have been defined and new insight into the role of JNK in survival signaling, cell death, cancer and diabetes has been achieved.




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