RGD Reference Report - Short-term fasting differentially alters PACAP and VIP levels in the brains of rat and chicken. - Rat Genome Database

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Short-term fasting differentially alters PACAP and VIP levels in the brains of rat and chicken.

Authors: Jozsa, R  Nemeth, J  Tamas, A  Hollosy, T  Lubics, A  Jakab, B  Olah, A  Lengvari, I  Arimura, A  Reglodi, D 
Citation: Jozsa R, etal., Ann N Y Acad Sci. 2006 Jul;1070:354-8.
RGD ID: 2325296
Pubmed: PMID:16888191   (View Abstract at PubMed)
DOI: DOI:10.1196/annals.1317.044   (Journal Full-text)

The present article investigated the levels of pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal polypeptide (VIP) in the brains of rats and chickens 12, 36, and 84 h after starvation. PACAP levels increased in both species, 12 h after food deprivation in rats, and with a 24-h delay in chickens. VIP levels showed a more complex pattern: a gradual increase in the hypothalamus and telencephalon, and a significant decrease in the brain stem of rats. In chickens, a decrease was observed in every brain area after 36 h of starvation. These data show that PACAP and VIP are differentially regulated and are involved in the regulatory processes under a food-restricted regimen, and are differentially altered in nocturnal and diurnal species.

Gene Ontology Annotations    Click to see Annotation Detail View

Biological Process
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
response to starvation  IEP 2325296 RGD 

Objects Annotated

Genes (Rattus norvegicus)
Adcyap1  (adenylate cyclase activating polypeptide 1)


Additional Information