RGD Reference Report - [Tissue-specific features of the pentose phosphate pathway in rats under acute alcoholic intoxication conditions] - Rat Genome Database

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[Tissue-specific features of the pentose phosphate pathway in rats under acute alcoholic intoxication conditions]

Authors: Lelevich, SV 
Citation: Lelevich SV Eksp Klin Farmakol. 2008 Mar-Apr;71(2):53-5.
RGD ID: 2307354
Pubmed: PMID:18488910   (View Abstract at PubMed)

The activity of pentose phosphate pathway (PPP) in the liver and skeletal muscles of rats has been studied after acute alcohol administration in a dose of 1, 2.5, and 5 g/kg body weight. Inhibition of the activity of the main PPP enzymes as well as a decrease in the liver pentose level in rats as a result of alcohol intoxication have been observed. In muscle tissues, alcohol leads to the activation of glucose-6-phosphate-dehydrogenase and the inhibition of the transketolase activity.

Gene Ontology Annotations    Click to see Annotation Detail View

Biological Process
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
response to ethanol  IDA 2307354 RGD 

Objects Annotated

Genes (Rattus norvegicus)
G6pd  (glucose-6-phosphate dehydrogenase)


Additional Information