RGD Reference Report - Polski tygodnik lekarski (Warsaw, Poland : 1960) - Rat Genome Database

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Polski tygodnik lekarski (Warsaw, Poland : 1960)

Authors: Kopieczna-Grzebieniak, E  Drozdz, M  Grabowska-Bochenek, R  Piekarski, M 
Citation: Kopieczna-Grzebieniak E, etal., Pol Tyg Lek. 1992 Jan 6-13;47(1-2):12-4.
RGD ID: 1625534
Pubmed: PMID:1384011   (View Abstract at PubMed)

The study was aimed at verification of previously found, in animals with experimentally induced atherosclerosis, the disturbances of serum proteinases inhibitors: alpha-2-antiplasmin, alpha-1-antitrypsin and alpha-2-macroglobulin. In humans with hypercholesterolemia the decrease of serum activity of alpha-2-antiplasmin was observed. In humans with hypercholesterolemia and increased serum concentration of triacylglycerols no significant changes in activity of alpha-1-antitrypsin and alpha-2-macroglobulin were found--in comparison with control subjects.

RGD Manual Disease Annotations    Click to see Annotation Detail View
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
Hypercholesterolemia  IEP 1625534protein:decreased expression:serumRGD 
Hypercholesterolemia  ISOSERPINF2 (Homo sapiens)1625534; 1625534protein:decreased expression:serumRGD 

Objects Annotated

Genes (Rattus norvegicus)
Serpinf2  (serpin family F member 2)

Genes (Mus musculus)
Serpinf2  (serine (or cysteine) peptidase inhibitor, clade F, member 2)

Genes (Homo sapiens)
SERPINF2  (serpin family F member 2)


Additional Information