RGD Reference Report - Circulating matrix metalloproteinase-1 and -3 in patients with an acute coronary syndrome. - Rat Genome Database

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Circulating matrix metalloproteinase-1 and -3 in patients with an acute coronary syndrome.

Authors: Inoue, T  Kato, T  Takayanagi, K  Uchida, T  Yaguchi, I  Kamishirado, H  Morooka, S  Yoshimoto, N 
Citation: Inoue T, etal., Am J Cardiol. 2003 Dec 15;92(12):1461-4.
RGD ID: 1582536
Pubmed: PMID:14675588   (View Abstract at PubMed)

To elucidate the diagnostic value of serum matrix metalloproteinase (MMP) levels, we measured MMP-1 and MMP-3 by a 1-step sandwich enzyme immunoassay. The transcardiac gradients of both MMPs were greater in patients with unstable angina and acute myocardial infarction than in patients with stable effort angina or control patients. Serum MMP levels appear to be a marker of plaque instability in patients with acute coronary syndrome.

RGD Manual Disease Annotations    Click to see Annotation Detail View
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
intermediate coronary syndrome  IDA 1582536 RGD 
intermediate coronary syndrome  ISOMMP1 (Homo sapiens)1582536; 1582536 RGD 

Objects Annotated

Genes (Rattus norvegicus)
Mmp1  (matrix metallopeptidase 1)

Genes (Mus musculus)
Mmp1a  (matrix metallopeptidase 1a (interstitial collagenase))

Genes (Homo sapiens)
MMP1  (matrix metallopeptidase 1)


Additional Information