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Circulating matrix metalloproteinase-1 and -3 in patients with an acute coronary syndrome.

Authors: Inoue, T  Kato, T  Takayanagi, K  Uchida, T  Yaguchi, I  Kamishirado, H  Morooka, S  Yoshimoto, N 
Citation: Inoue T, etal., Am J Cardiol. 2003 Dec 15;92(12):1461-4.
Pubmed: (View Article at PubMed) PMID:14675588

To elucidate the diagnostic value of serum matrix metalloproteinase (MMP) levels, we measured MMP-1 and MMP-3 by a 1-step sandwich enzyme immunoassay. The transcardiac gradients of both MMPs were greater in patients with unstable angina and acute myocardial infarction than in patients with stable effort angina or control patients. Serum MMP levels appear to be a marker of plaque instability in patients with acute coronary syndrome.


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RGD Object Information
RGD ID: 1582536
Created: 2006-11-13
Species: All species
Last Modified: 2006-11-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.