RGD Reference Report - Chromosomal location of fifteen unique mouse KRAB-containing zinc finger loci. - Rat Genome Database

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Chromosomal location of fifteen unique mouse KRAB-containing zinc finger loci.

Authors: Marine, JC  Gilbert, DJ  Bellefroid, EJ  Martial, JA  Ihle, JN  Copeland, NG  Jenkins, NA 
Citation: Marine JC, etal., Mamm Genome 1996 Jun;7(6):413-6.
RGD ID: 1556694
Pubmed: PMID:8662221   (View Abstract at PubMed)

The mammalian genome contains hundreds if not thousands of zinc finger protein (Zfp) genes. While the function of most of these genes remains to be determined, it is clear that a few of them play important roles in gene regulation and development. In studies described here, we have used an interspecific mouse backcross mapping panel to determine the chromosomal location of 15 KRAB-containing zinc finger loci. These loci map to nine different mouse autosomes and the X Chromosome (Chr). Two Chrs, 7 and 9, contain cosegregating pairs of KRAB-containing Zfp genes, indicating that the KRAB-containing Zfp genes have evolved through processes involving regional as well as genome-wide duplication events.

Objects referenced in this article
Gene Araf Araf proto-oncogene, serine/threonine kinase Mus musculus
Gene Csf3r colony stimulating factor 3 receptor Mus musculus
Gene Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 Mus musculus
Gene Kcna4 potassium voltage-gated channel, shaker-related subfamily, member 4 Mus musculus
Gene Mas1 MAS1 oncogene Mus musculus
Gene Nr3c2 nuclear receptor subfamily 3, group C, member 2 Mus musculus
Gene Pth parathyroid hormone Mus musculus
Gene Rasa1 RAS p21 protein activator 1 Mus musculus
Gene Tymp thymidine phosphorylase Mus musculus
Gene Zfp143 zinc finger protein 143 Mus musculus
Gene Zfp26 zinc finger protein 26 Mus musculus
Gene Zfp317 zinc finger protein 317 Mus musculus
Gene Zfp426 zinc finger protein 426 Mus musculus
Gene Zfp52 zinc finger protein 52 Mus musculus
Gene Zfp54 zinc finger protein 54 Mus musculus
Gene Zfp68 zinc finger protein 68 Mus musculus
Gene Zfp69 zinc finger protein 69 Mus musculus
Gene Zfp7 zinc finger protein 7 Mus musculus
Gene Zfp74 zinc finger protein 74 Mus musculus
Gene Zfp84 zinc finger protein 84 Mus musculus

Additional Information