RGD Reference Report - Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. - Rat Genome Database

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Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.

Authors: Brady, KP  Rowe, LB  Her, H  Stevens, TJ  Eppig, J  Sussman, DJ  Sikela, J  Beier, DR 
Citation: Brady KP, etal., Genome Res 1997 Nov;7(11):1085-93.
RGD ID: 1549511
Pubmed: PMID:9371744   (View Abstract at PubMed)
PMCID: PMC310685   (View Article at PubMed Central)

We have demonstrated previously that noncoding sequences of genes are a robust source of polymorphisms between mouse species when tested using single-strand conformation polymorphism (SSCP) analysis, and that these polymorphisms are useful for genetic mapping. In this report we demonstrate that presumptive 3'-untranslated region sequence obtained from expressed sequence tags (ESTs) can be analyzed in a similar fashion, and we have used this approach to map 262 loci using an interspecific backcross. These results demonstrate SSCP analysis of genes or ESTs is a simple and efficient means for the genetic localization of transcribed sequences, and is furthermore an approach that is applicable to any system for which there is sufficient sequence polymorphism.



Objects referenced in this article
Gene Aamp angio-associated migratory protein Mus musculus
Gene Abr active BCR-related gene Mus musculus
Gene Aco2 aconitase 2, mitochondrial Mus musculus
Gene Acvr2a activin receptor IIA Mus musculus
Gene Adarb1 adenosine deaminase, RNA-specific, B1 Mus musculus
Gene Adcy1 adenylate cyclase 1 Mus musculus
Gene Agt angiotensinogen Mus musculus
Gene Ahcyl1 S-adenosylhomocysteine hydrolase-like 1 Mus musculus
Gene Ahi1 Abelson helper integration site 1 Mus musculus
Gene Aip aryl-hydrocarbon receptor-interacting protein Mus musculus
Gene Akr7a5 aldo-keto reductase family 7, member A5 Mus musculus
Gene Anxa5 annexin A5 Mus musculus
Gene Anxa7 annexin A7 Mus musculus
Gene Apbb1 amyloid beta precursor protein binding family B member 1 Mus musculus
Gene Arhgef28 Rho guanine nucleotide exchange factor 28 Mus musculus
Gene Atp5f1b ATP synthase F1 subunit beta Mus musculus
Gene Atp5mc1 ATP synthase membrane subunit c locus 1 Mus musculus
Gene Atp5pb ATP synthase peripheral stalk-membrane subunit b Mus musculus
Gene Atp5pf ATP synthase peripheral stalk subunit F6 Mus musculus
Gene Atp6v0c ATPase, H+ transporting, lysosomal V0 subunit C Mus musculus
Gene Btc betacellulin, epidermal growth factor family member Mus musculus
Gene Btg2 BTG anti-proliferation factor 2 Mus musculus
Gene Calm1 calmodulin 1 Mus musculus
Gene Cbln1 cerebellin 1 precursor protein Mus musculus
Gene Ccl7 C-C motif chemokine ligand 7 Mus musculus
Gene Cd36 CD36 molecule Mus musculus
Gene Cdc42ep2 CDC42 effector protein 2 Mus musculus
Gene Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase Mus musculus
Gene Cdk5r1 cyclin dependent kinase 5, regulatory subunit 1 Mus musculus
Gene Chka choline kinase alpha Mus musculus
Gene Cmas cytidine monophospho-N-acetylneuraminic acid synthetase Mus musculus
Gene Cntn1 contactin 1 Mus musculus
Gene Col6a1 collagen, type VI, alpha 1 Mus musculus
Gene Cox4i1 cytochrome c oxidase subunit 4I1 Mus musculus
Gene Cox6a1 cytochrome c oxidase subunit 6A1 Mus musculus
Gene Crmp1 collapsin response mediator protein 1 Mus musculus
Gene Cst3 cystatin C Mus musculus
Gene Cx3cl1 C-X3-C motif chemokine ligand 1 Mus musculus
Gene Dbh dopamine beta hydroxylase Mus musculus
Gene Dlgap1 DLG associated protein 1 Mus musculus
Gene Dlk1 delta like non-canonical Notch ligand 1 Mus musculus
Gene Dnajc17 DnaJ heat shock protein family (Hsp40) member C17 Mus musculus
Gene Dnase1 deoxyribonuclease I Mus musculus
Gene Dut deoxyuridine triphosphatase Mus musculus
Gene Egln2 egl-9 family hypoxia-inducible factor 2 Mus musculus
Gene Fabp4 fatty acid binding protein 4, adipocyte Mus musculus
Gene Fgl2 fibrinogen-like protein 2 Mus musculus
Gene Fstl1 follistatin-like 1 Mus musculus
Gene Gadd45a growth arrest and DNA-damage-inducible 45 alpha Mus musculus
Gene Gadd45b growth arrest and DNA-damage-inducible 45 beta Mus musculus
Gene Gcg glucagon Mus musculus
Gene Gjb6 gap junction protein, beta 6 Mus musculus
Gene Gnai1 G protein subunit alpha i1 Mus musculus
Gene Gpr12 G-protein coupled receptor 12 Mus musculus
Gene Gpr83 G protein-coupled receptor 83 Mus musculus
Gene Gpx1 glutathione peroxidase 1 Mus musculus
Gene Grn granulin Mus musculus
Gene Hnrnpc heterogeneous nuclear ribonucleoprotein C Mus musculus
Gene Ifrd1 interferon-related developmental regulator 1 Mus musculus
Gene Il10ra interleukin 10 receptor, alpha Mus musculus
Gene Kif1c kinesin family member 1C Mus musculus
Gene Kif5a kinesin family member 5A Mus musculus
Gene Kpna2 karyopherin subunit alpha 2 Mus musculus
Gene Ldhd lactate dehydrogenase D Mus musculus
Gene Lrig1 leucine-rich repeats and immunoglobulin-like domains 1 Mus musculus
Gene Maged1 MAGE family member D1 Mus musculus
Gene Mapk3 mitogen-activated protein kinase 3 Mus musculus
Gene Mpp2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) Mus musculus
Gene Mrpl34 mitochondrial ribosomal protein L34 Mus musculus
Gene Mrpl49 mitochondrial ribosomal protein L49 Mus musculus
Gene Mtg2 mitochondrial ribosome associated GTPase 2 Mus musculus
Gene Ndrg4 N-myc downstream regulated gene 4 Mus musculus
Gene Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 Mus musculus
Gene Ngef neuronal guanine nucleotide exchange factor Mus musculus
Gene Nop2 NOP2 nucleolar protein Mus musculus
Gene Nptx1 neuronal pentraxin 1 Mus musculus
Gene Nptxr neuronal pentraxin receptor Mus musculus
Gene Nrxn3 neurexin III Mus musculus
Gene Orm1 orosomucoid 1 Mus musculus
Gene Pax8 paired box 8 Mus musculus
Gene Pebp1 phosphatidylethanolamine binding protein 1 Mus musculus
Gene Pin1 peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1 Mus musculus
Gene Pkm pyruvate kinase, muscle Mus musculus
Gene Plpp3 phospholipid phosphatase 3 Mus musculus
Gene Plxnb2 plexin B2 Mus musculus
Gene Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma Mus musculus
Gene Prdx1 peroxiredoxin 1 Mus musculus
Gene Prkar1b protein kinase, cAMP dependent regulatory, type I beta Mus musculus
Gene Prkcsh protein kinase C substrate 80K-H Mus musculus
Gene Prmt1 protein arginine N-methyltransferase 1 Mus musculus
Gene Prpf8 pre-mRNA processing factor 8 Mus musculus
Gene Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 Mus musculus
Gene Ptbp1 polypyrimidine tract binding protein 1 Mus musculus
Gene Ptger3 prostaglandin E receptor 3 (subtype EP3) Mus musculus
Gene Ptk2 PTK2 protein tyrosine kinase 2 Mus musculus
Gene Purb purine rich element binding protein B Mus musculus
Gene Rab6b RAB6B, member RAS oncogene family Mus musculus
Gene Rad51 RAD51 recombinase Mus musculus
Gene Ralbp1 ralA binding protein 1 Mus musculus
Gene Relb avian reticuloendotheliosis viral (v-rel) oncogene related B Mus musculus
Gene Rims2 regulating synaptic membrane exocytosis 2 Mus musculus
Gene Ripk2 receptor (TNFRSF)-interacting serine-threonine kinase 2 Mus musculus
Gene Rufy2 RUN and FYVE domain-containing 2 Mus musculus
Gene Sars1 seryl-tRNA synthetase 1 Mus musculus
Gene Sec23a SEC23 homolog A, COPII coat complex component Mus musculus
Gene Sgsm1 small G protein signaling modulator 1 Mus musculus
Gene Sirpa signal-regulatory protein alpha Mus musculus
Gene Slc1a3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 Mus musculus
Gene Slc25a26 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26 Mus musculus
Gene Slc25a4 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 Mus musculus
Gene Slc7a10 solute carrier family 7 (cationic amino acid transporter, y+ system), member 10 Mus musculus
Gene Slx4 SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) Mus musculus
Gene Snrk SNF related kinase Mus musculus
Gene Snrpn small nuclear ribonucleoprotein N Mus musculus
Gene Sparcl1 SPARC-like 1 Mus musculus
Gene Speg SPEG complex locus Mus musculus
Gene Syn2 synapsin II Mus musculus
Gene Tbxas1 thromboxane A synthase 1, platelet Mus musculus
Gene Tcf12 transcription factor 12 Mus musculus
Gene Tenm2 teneurin transmembrane protein 2 Mus musculus
Gene Tfb2m transcription factor B2, mitochondrial Mus musculus
Gene Timp2 tissue inhibitor of metalloproteinase 2 Mus musculus
Gene Timp3 tissue inhibitor of metalloproteinase 3 Mus musculus
Gene Tpm1 tropomyosin 1, alpha Mus musculus
Gene Trap1 TNF receptor-associated protein 1 Mus musculus
Gene Tshz1 teashirt zinc finger family member 1 Mus musculus
Gene Tspyl2 TSPY-like 2 Mus musculus
Gene Tspyl4 TSPY-like 4 Mus musculus
Gene Ttc17 tetratricopeptide repeat domain 17 Mus musculus
Gene Tuba1a tubulin, alpha 1A Mus musculus
Gene Tubb2a tubulin, beta 2A class IIA Mus musculus
Gene Tubg1 tubulin, gamma 1 Mus musculus
Gene Ube2h ubiquitin-conjugating enzyme E2H Mus musculus
Gene Ube2m ubiquitin-conjugating enzyme E2M Mus musculus
Gene Ube4b ubiquitination factor E4B Mus musculus
Gene Ubxn11 UBX domain protein 11 Mus musculus
Gene Unc5b unc-5 netrin receptor B Mus musculus
Gene Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 Mus musculus
Gene Uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII Mus musculus
Gene Usp4 ubiquitin specific peptidase 4 (proto-oncogene) Mus musculus
Gene Vamp1 vesicle-associated membrane protein 1 Mus musculus
Gene Wdr45b WD repeat domain 45B Mus musculus
Gene Wnt5a wingless-type MMTV integration site family, member 5A Mus musculus
Gene Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide Mus musculus
Gene Zfp28 zinc finger protein 28 Mus musculus
Gene Zfp36 zinc finger protein 36 Mus musculus

Additional Information