RGD Reference Report - Comparative FISH mapping of mouse and rat homologues of twenty-five human X-linked genes. - Rat Genome Database

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Comparative FISH mapping of mouse and rat homologues of twenty-five human X-linked genes.

Authors: Kuroiwa, A  Watanabe, T  Hishigaki, H  Takahashi, E  Namikawa, T  Matsuda, Y 
Citation: Kuroiwa A, etal., Cytogenet Cell Genet 1998;81(3-4):208-12.
RGD ID: 1300495
Pubmed: PMID:9730605   (View Abstract at PubMed)

We constructed a comparative cytogenetic map of 25 functional genes in mouse and rat X chromosomes by direct R-banding fluorescence in situ hybridization. Nineteen and 22 out of the 25 genes, which have been mapped on the human X chromosome, were newly localized to mouse and rat X chromosomes, respectively. Twenty-two additional genes were integrated in the rat-mouse-human comparative map of the X chromosome in this study. Comparison of the gene order indicated the presence of four chromosome segments with conserved linkage homology between mouse and rat X chromosomes, suggesting that a minimum of four chromosomal inversion events occurred between mouse and rat X chromosomes during the evolution of the two species. Four chromosome segments with conserved linkage homology were found between human and rat X chromosomes.

Objects referenced in this article
Gene Araf Araf proto-oncogene, serine/threonine kinase Mus musculus
Gene Bgn biglycan Mus musculus
Gene Cetn2 centrin 2 Mus musculus
Gene Elk1 ELK1, member of ETS oncogene family Mus musculus
Gene Fhl1 four and a half LIM domains 1 Mus musculus
Gene Gdi1 GDP dissociation inhibitor 1 Mus musculus
Gene Idh3g isocitrate dehydrogenase 3 (NAD+), gamma Mus musculus
Gene Pdha1 pyruvate dehydrogenase E1 alpha 1 Mus musculus
Gene Phka2 phosphorylase kinase alpha 2 Mus musculus
Gene Piga phosphatidylinositol glycan anchor biosynthesis, class A Mus musculus
Gene Plp2 proteolipid protein 2 Mus musculus
Gene Plxna3 plexin A3 Mus musculus
Gene Sat1 spermidine/spermine N1-acetyl transferase 1 Mus musculus
Gene Slc25a5 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 Mus musculus
Gene Sox3 SRY (sex determining region Y)-box 3 Mus musculus
Gene Tafazzin tafazzin, phospholipid-lysophospholipid transacylase Mus musculus
Gene Tspan7 tetraspanin 7 Rattus norvegicus

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