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Gustducin is a taste-cell-specific G protein closely related to the transducins.

Authors: McLaughlin, SK  McKinnon, PJ  Margolskee, RF 
Citation: McLaughlin SK, etal., Nature 1992 Jun 18;357(6379):563-9.
Pubmed: (View Article at PubMed) PMID:1608467
DOI: Full-text: DOI:10.1038/357563a0

A novel G protein alpha-subunit (alpha-gustducin) has been identified and cloned from taste tissue. alpha-Gustducin messenger RNA is expressed in taste buds of all taste papillae (circumvallate, foliate and fungiform); it is not expressed in non-sensory portions of the tongue, nor is it expressed in the other tissues examined. alpha-Gustducin most closely resembles the transducins (the rod and cone photoreceptor G proteins), suggesting that gustducin's role in taste transduction is analogous to that of transducin in light transduction.


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RGD Object Information
RGD ID: 1299560
Created: 2004-06-01
Species: All species
Last Modified: 2006-04-25
Status: ACTIVE


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