RGD Reference Report - The inv(3)(q21q26)/t(3;3)(q21;q26) is frequently accompanied by alterations of the RUNX1, KRAS and NRAS and NF1 genes and mediates adverse prognosis both in MDS and in AML: a study in 39 cases of MDS or AML. - Rat Genome Database

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The inv(3)(q21q26)/t(3;3)(q21;q26) is frequently accompanied by alterations of the RUNX1, KRAS and NRAS and NF1 genes and mediates adverse prognosis both in MDS and in AML: a study in 39 cases of MDS or AML.

Authors: Haferlach, C  Bacher, U  Haferlach, T  Dicker, F  Alpermann, T  Kern, W  Schnittger, S 
Citation: Haferlach C, etal., Leukemia. 2011 May;25(5):874-7. doi: 10.1038/leu.2011.5. Epub 2011 Feb 1.
RGD ID: 11060151
Pubmed: PMID:21283084   (View Abstract at PubMed)
DOI: DOI:10.1038/leu.2011.5   (Journal Full-text)

Abstract for this paper unavailable

RGD Manual Disease Annotations    Click to see Annotation Detail View

Objects Annotated

Genes (Rattus norvegicus)
Kras  (KRAS proto-oncogene, GTPase)
Nras  (NRAS proto-oncogene, GTPase)

Genes (Mus musculus)
Kras  (Kirsten rat sarcoma viral oncogene homolog)
Nras  (neuroblastoma ras oncogene)

Genes (Homo sapiens)
KRAS  (KRAS proto-oncogene, GTPase)
NRAS  (NRAS proto-oncogene, GTPase)


Additional Information