Edpm10 QTL Report (Rattus norvegicus)

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QTL Registration

General

QTL: Edpm10 (Estrogen-dependent pituitary mass QTL 10) Rattus norvegicus
Symbol:	Edpm10
Name:	Estrogen-dependent pituitary mass QTL 10
RGD ID:	737856
Previously known as:	suggestive QTL on Chr 14
Trait:	pituitary gland mass (VT:0010496)
Measurement Type:	pituitary gland wet weight (CMO:0000853)
LOD Score:	2.83
P Value:	Not Available
Variance:	6.5
Position	No map positions available.
Cross Type:	intercross
Strains Crossed:	BN/SsNHsd F344/NHsd

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Pituitary Neoplasms (IAGP)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

pituitary gland hyperplasia (QTM)

Experimental Data Annotations Click to see Annotation Detail View

Clinical Measurement

pituitary gland wet weight (IDA)

Experimental Condition

diethylstilbestrol (IDA)

surgical implantation (IDA)

Measurement Method

post excision weight measurement (IDA)

Vertebrate Trait

pituitary gland mass (IDA)

Rat Strain

BN/SsNHsd (IEA)

F344/NHsd (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Quantitative trait loci for estrogen-dependent pituitary tumor growth in the rat.	Wendell DL and Gorski J, Mamm Genome 1997;8(11):823-9

Region

Markers in Region

The following Markers overlap with this region.

RGD ID

Symbol

Expected Size

Chr

Start

Stop

Species

Match

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	Edpm10

RGD Curation Notes

Note Type	Note	Reference
qtl_cross_type	intercross
qtl_general	BN allele is associated with increased estrogen-dependent pituitary mass	61074
qtl_general	moderate interaction in noticed between Edpm5 and Edpm10 (P=0.016) which is associated with estrogen-dependent pituitary mass	61074

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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QTL: Edpm10 (Estrogen-dependent pituitary mass QTL 10) Rattus norvegicus

Mammalian Phenotype