Gdil1 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Gdil1 (Gastrointestinal dilation QTL 1) Rattus norvegicus

Symbol: Gdil1
Name: Gastrointestinal dilation QTL 1
RGD ID: 6480225
Previously known as: Lrag1; Locus of resistance to aganglionosis 1
Trait: enteric ganglion morphology trait   (VT:0001045)    
Measurement Type: length of intestine affected by colonic aganglionosis to total length of colon ratio   (CMO:0001836)    
LOD Score: LRS:23.9
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2256,660,879 - 74,786,777RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0258,344,100 - 75,687,607RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0276,649,726 - 95,410,202RGDRnor5.0
RGSC_v3.4257,161,998 - 75,806,439RGDRGSC3.4
Cross Type: intercross
Strains Crossed: AR-Ednrbsl/Hkv F344.AR-Ednrbsl/Hkv 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
Gdnf is a candidate Gene for Gdil1
Rai14 is a candidate Gene for Gdil1

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. QTL analysis identifies a modifier locus of aganglionosis in the rat model of Hirschsprung disease carrying Ednrb(sl) mutations. Dang R, etal., PLoS One. 2011;6(11):e27902. Epub 2011 Nov 22.
2. Genetic background strongly modifies the severity of symptoms of Hirschsprung disease, but not hearing loss in rats carrying Ednrb(sl) mutations. Dang R, etal., PLoS One. 2011;6(9):e24086. Epub 2011 Sep 7.
3. Identification of genetic loci affecting the severity of symptoms of Hirschsprung disease in rats carrying Ednrbsl mutations by quantitative trait locus analysis. Huang J, etal., PLoS One. 2015 Mar 19;10(3):e0122068. doi: 10.1371/journal.pone.0122068. eCollection 2015.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
2322Cdh6cadherin 626207913962225228Rat
619958Pdzd2PDZ domain containing 226138461461770516Rat
619741Cdh10cadherin 1026862862368850995Rat
3196Npr3natriuretic peptide receptor 326086548360933432Rat
3407Prlrprolactin receptor25913414759324719Rat
2677Gdnfglial cell derived neurotrophic factor25689399256919935Rat
621226Golph3golgi phosphoprotein 326134803061376051Rat
620450Spef2sperm flagellar 225851248958694718Rat
621582Sub1SUB1 regulator of transcription26100564661020486Rat
621729Dnajc21DnaJ heat shock protein family (Hsp40) member C2125941950559446743Rat
621199Nup155nucleoporin 15525720131057252918Rat
621767Agxt2alanine-glyoxylate aminotransferase 225933625259377664Rat
3048Amacralpha-methylacyl-CoA racemase25994615859958255Rat
1306809Nadk2NAD kinase 2, mitochondrial25811767458159815Rat
1305010C1qtnf3C1q and TNF related 325991709959939519Rat
1306393NipblNIPBL, cohesin loading factor25739944357586770Rat
1307323Adamts12ADAM metallopeptidase with thrombospondin type 1 motif, 1226003287360327629Rat
1308508Brix1biogenesis of ribosomes BRX125945060859461486Rat
1306690Slc45a2solute carrier family 45, member 225996359959996408Rat
3698Slc1a3solute carrier family 1 member 325775549557830605Rat
1309776Il7rinterleukin 7 receptor25845239358477757Rat
1311550Rxfp3relaxin family peptide receptor 326000325660004686Rat
1307626Droshadrosha ribonuclease III26186488661976688Rat
1311890Zfrzinc finger RNA binding protein26113761161200322Rat
1305942Rai14retinoic acid induced 1425954628459682687Rat
1310081Cplane1ciliogenesis and planar polarity effector complex subunit 125726919557369580Rat
1309487Wdr70WD repeat domain 7025695134557191244Rat
1307559Ranbp3lRAN binding protein 3-like25805788758113158Rat
1306496Rad1RAD1 checkpoint DNA exonuclease25946159759469707Rat
1306502RGD1306502similar to hypothetical protein FLJ1119326184871661864762Rat
1305430Cdh18cadherin 1827281807673820144Rat
1308776Capslcalcyphosine-like25839499558425527Rat
1308343Cdh9cadherin 926628042266367121Rat
1307902Mtmr12myotubularin related protein 1226122371461293266Rat
1564928Ttc23ltetratricopeptide repeat domain 23-like25947666659538313Rat
1563920Lmbrd2LMBR1 domain containing 225818955858251565Rat
1562936Hsp90ab1-ps6heat shock protein 90 alpha family class B member 1, pseudogene 627212525172129162Rat
1564125RGD1564125similar to Cln5 protein26589349565902741Rat
1562456Skp2S-phase kinase associated protein 225816122658189293Rat
1561906RGD1561906similar to RIKEN cDNA 4930430F0827298438872986671Rat
1585807Knop1-ps1lysine-rich nucleolar protein 1, pseudogene 126567090865672736Rat
1583285Hspd1-ps25heat shock protein family D (Hsp60) member 1, pseudogene 2527460975074613329Rat
1566350Cdh12cadherin 1227047467971705369Rat
1564365Ugt3a2UDP glycosyltransferase 3 family, polypeptide A225832705858350186Rat
1592966Setd3-ps2SET domain containing 3, actin histidine methyltransferase, pseudogene 226045263060453393Rat
1586190Ube2r2-ps1ubiquitin-conjugating enzyme E2R 2, pseudogene 126955210069554245Rat
1583619Rps2-ps9ribosomal protein S2, pseudogene 925810144858102404Rat
1359527Tars1threonyl-tRNA synthetase 126036825160387733Rat
1583588Snap23-ps1synaptosome associated protein 23, pseudogene 126760413067609584Rat
1593220Smarce1-ps11SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1, pseudogene 1126941461569417238Rat
1596656Dda1-ps1DET1- and DDB1-associated 1, pseudogene 127382393973841395Rat
1594499Snw1-ps1SNW domain containing 1, pseudogene 125674032056741899Rat
1594163Dbi-ps2diazepam binding inhibitor, acyl-CoA binding protein, pseudogene 226066996860670245Rat
1596810Ugt3a2-ps2UDP glycosyltransferase 3 family, polypeptide A2, pseudogene 225831491258327069Rat
1594378Nono-ps8non-POU domain containing, octamer-binding, pseudogene 825738143957382974Rat
2322932Ubap2-ps1ubiquitin-associated protein 2, pseudogene 126600754266009900Rat
2323466Riox2-ps3ribosomal oxygenase 2, pseudogene 326393638763937165Rat
2323519Oip5-ps1Opa interacting protein 5, pseudogene 126359223363595295Rat
2323951LOC100362827high-mobility group nucleosomal binding domain 2-like25761869057618983Rat
2324086Rps12-ps3ribosomal protein S12, pseudogene25761507957615691Rat
2324713Ftl1-ps14ferritin light chain 1, pseudogene 1426154356361544581Rat
6492359Klra5-ps1killer cell lectin-like receptor, subfamily A, member 5, pseudogene 126421267264217862Rat
6495770Hnrnpa1-ps29heterogeneous nuclear ribonucleoprotein A1, pseudogene 2925729338457298637Rat
6504200LOC100909396uncharacterized LOC10090939626182809661830209Rat
7505957LOC102553625uncharacterized LOC10255362526877889068939928Rat
7503607Mrpl40-ps1mitochondrial ribosomal protein L40, pseudogene 125946985759471850Rat
7662910LOC102552232uncharacterized LOC10255223226576716665819676Rat
7662935LOC102553734uncharacterized LOC10255373426898029469020038Rat
7655727LOC102554147uncharacterized LOC10255414727215668172198344Rat
41054385LOC120101168U6 spliceosomal RNA26108224061082346Rat
7667725Hnrnpa1-ps52heterogeneous nuclear ribonucleoprotein A1, pseudogene 5227324733073249760Rat
9200405LOC103691481uncharacterized LOC10369148125770176757704913Rat
9387191LOC103691483uncharacterized LOC10369148325973429159747359Rat
9362373LOC103695100uncharacterized LOC10369510026207365762085399Rat
11453461LOC108350230glyceraldehyde-3-phosphate dehydrogenase pseudogene26273716662738204Rat
11388086Rpl23-ps4ribosomal protein L23,pseudogene 425753907957542026Rat
11378090LOC10835022960S ribosomal protein L17 pseudogene25984172659842316Rat
11382166LOC108349962uncharacterized LOC10834996225783544257840143Rat
11511747LOC108350170glyceraldehyde-3-phosphate dehydrogenase pseudogene26084791860848940Rat
11493630LOC10835017160S ribosomal protein L7a pseudogene26242432862430752Rat
41111255LOC120100737E3 SUMO-protein ligase KIAA1586-like25853208058540473Rat
41276753LOC120100740uncharacterized LOC12010074025960122159605292Rat
41250842LOC120100745uncharacterized LOC12010074526853932368628612Rat
41324318LOC120100741uncharacterized LOC12010074126001648260032748Rat
41357925LOC12010099860S ribosomal protein L6-like26813098468132284Rat
41384167Ube2n-ps8ubiquitin-conjugating enzyme E2N, pseudogene 826977182569772236Rat
41207236LOC120100736uncharacterized LOC12010073625810997758118986Rat
41287396Trnav-aac30transfer RNA valine (anticodon AAC) 3027284242772842507Rat
41261285LOC120101395U1 spliceosomal RNA27406126874061423Rat
41178470LOC120100559uncharacterized LOC12010055925877866258796834Rat
41123498LOC120101245small nucleolar RNA SNORA4427044660770446735Rat
41180045LOC120101302small nucleolar RNA SNORA1727347496673475097Rat
41191856LOC120101085uncharacterized LOC12010108526102048861021424Rat
41213708LOC120101118U2 spliceosomal RNA25692982556930018Rat
41397082LOC120100738uncharacterized LOC12010073825862629358669887Rat
41102832LOC120101346small nucleolar RNA SNORA1727094241070942533Rat
41127911Nono-ps5non-POU domain containing, octamer-binding, pseudogene 525875832858760040Rat
41184907LOC120101260small nucleolar RNA SNORA4825946698059467107Rat
41196986LOC120101348small nucleolar RNA SNORA1726516063165160712Rat
41400978LOC120100747uncharacterized LOC12010074727214718872156686Rat
41294127Ubap2-ps2ubiquitin-associated protein 2, pseudogene 226600528266007542Rat
41403201LOC120101087uncharacterized LOC12010108727050893070511875Rat
41231663Dpp3-ps3dipeptidyl peptidase 3, pseudogene 226429759364432049Rat
41232314Rpl13-ps13ribosomal protein L13, pseudogene 1326459573764596270Rat
40934801Dpy30-ps1dpy-30 histone methyltransferase complex regulatory subunit, pseudogene 125952263859526672Rat
40962450LOC120101086uncharacterized LOC12010108626132407061330556Rat
40941042LOC120100734uncharacterized LOC12010073425722934357230048Rat
40994045Rpl9-ps4ribosomal protein L9, pseudogene 425739033357399288Rat
40994990LOC120100997protein crumbs homolog 3-like26800073868003782Rat
40995943LOC120100742uncharacterized LOC12010074226558793765606771Rat
41024443LOC120101173U6 spliceosomal RNA26280651762806619Rat
41135571LOC120100560uncharacterized LOC12010056026902009469020818Rat
41335676Rbbp9-ps1RB binding protein 9, serine hydrolase, pseudogene 126867700268677554Rat
41315512Fus-ps4FUS RNA binding protein, pseudogene 427413938274141230Rat
41337724LOC120100746uncharacterized LOC12010074626865085668670949Rat
41066036LOC120101289small nucleolar RNA SNORA1726034044160340572Rat
41237332Rnu1-24RNA, U1 small nuclear 2427426084874261011Rat
41041387Pld6-ps1phospholipase D family, member 6, pseudogene 125702950057031550Rat
41241035Ugt3a2-ps1UDP glycosyltransferase 3 family, polypeptide A2, pseudogene 125838571458389680Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10319D2Mco4121227381172573811941Ratregion
11155D2Wox1418225932445459324636Ratregion
11156D2Mit2431025932437759324691Ratregion
33824D2Mit418826158212361582311Ratregion
34487D2Mgh330426251660962516896Ratregion
33739D2Mit531826611827566118463Ratregion
36017D2Rat7413026917384469173974Ratregion
35272D2Rat1914025760561257605741Ratregion
36850D2Rat2016025994328659943463Ratregion
35142D2Rat2212726846286068462973Ratregion
35643D2Rat2111327478666474786777Ratregion
40470D2Rat29917026353190063532066Ratregion
40560D2Rat27316327441756774417754Ratregion
40074D2Rat20713727305587573056016Ratregion
39046D2Rat17522325943983459440061Ratregion
39170D2Rat17418225974481759745001Ratregion
42117D2Arb4223026499184564992091Ratregion
42119D2Arb633525932430759324662Ratregion
42121D2Arb715025666087956661032Ratregion
42287D2Rat37120727387824373878442Ratregion
41188D2Rat20622226864256868642799Ratregion
42573D2Rat38523325752299657523239Ratregion
42576D2Rat27114526030523460305371Ratregion
42577D2Rat32020726185874561858937Ratregion
42578D2Rat32223927324535973245596Ratregion
42579D2Rat32320727355816973558384Ratregion
44552D9Wox2113627196810571968162Ratregion
43500D2Got18314426630034766300491Ratregion
43501D2Got4421327036780870368021Ratregion
60324D2Got4719126898344468983634Ratregion
67827D2Uwm2910726073165260731732Ratregion
66432D9Mco728526844340268443753Ratregion
66537D12Uia227025917270459172974Ratregion
67257D2Arb828025842920558429485Ratregion
67749D2Uwm3022626198885061989099Ratregion
1630974D2Got31411926111683761116951Ratregion
1632178D2Got31222425785740057857624Ratregion
1578914D2Chm29624427255502672555272Ratregion
1578947D2Chm28022125917985359180074Ratregion
1579111D2Chm29424126771746367717704Ratregion
1579114D2Chm29924227374444373744685Ratregion
1627859D2Got39728626244281862443104Ratregion
1628202D2Wox2913625875755058757686Ratregion
1628294D2Got40119426110233161102520Ratregion
1629043D2Got31617725996910259969279Ratregion
1629260D2Got38426525703039757030664Ratregion
1632736D2Got32014726404621364046360Ratregion
1632808D2Ulb714925979644859796597Ratregion
1633230D2Got31922226443107164431288Ratregion
1639805D2Got31329525710294157103236Ratregion
1635435D2Got31711826358755263587670Ratregion
1636242D2Got38027725996340259963675Ratregion
1636843D2Got30823725714186357142100Ratregion
1637376D2Got31510726027751160277618Ratregion
1634123D2Got31019525750176157501956Ratregion
7192180Prlr12025930626159306381Ratregion
5035787PMC17879P158326093163460932217Ratregion
5038880RH12738621925995793659958155Ratregion
5036761AU04911917026382061163820781Ratregion
5037031AU04998217126202042162020592Ratregion
5035542Mrpl40025947112759471615Ratregion
5029953BF40012520025866911958669319Ratregion
5027483AI5042999225780811557808207Ratregion
5030659BI30169816025717937057179530Ratregion
5025710RH12936120326119980461200010Ratregion
5054867RH14347117625731049257310668Ratregion
5054873RH14347421825778815057788368Ratregion
5054203RH14308926525730172357301988Ratregion
5054285RH14313621126100731961007530Ratregion
5055103RH14360726325816172358161986Ratregion
5058794BI27801919625717781057178006Ratregion
5059950BF38820419325808475558084948Ratregion
5053335RH14258911825725577757255895Ratregion
5052565AA58950825926793198967932248Ratregion
5052565AA58950825926793198967932248Ratregion
5050686RH13420019025718533957186096Ratregion
5053137RH14247529226207567362075965Ratregion
5051553AW12520510525841458658414691Ratregion
5054695RH14337217225739977757399949Ratregion
5041370RH12881818425816131258161496Ratregion
5046154RH13158918825975390459754092Ratregion
5047932RH13261220626129283261293038Ratregion
5048002RH13265220325954642859546631Ratregion
5049412RH13346621525946897459469476Ratregion
5047226RH13220620925945066759450875Ratregion
5039408RH12768919025937769459377884Ratregion
5039610RH12780418025825119158251371Ratregion
5039928RH12798820426793187467932078Ratregion
5039928RH12798820426793187467932078Ratregion
5040252RH12817721726100573261005947Ratregion
5043490RH13005521826088913460889352Ratregion
5076828RH13940212825725379457253922Ratregion
5076898RH13944315426566903865669208Ratregion
5077058RH13953519125775567757755868Ratregion
5074990RH13833515525770179157701946Ratregion
5077360RH13971218125945187859452059Ratregion
5076066RH13895921425725614157256355Ratregion
5075092RH13839312525736932257369447Ratregion
5075578RH13867512125815914658159267Ratregion
5078262RH14023718426924979369249977Ratregion
5078486RH14037013125775574457755875Ratregion
5080072RH14136718127424652074246703Ratregion
5071086RH13487821526086810960868324Ratregion
5078624RH14045113926271483462714974Ratregion
5070984RH13481919726207501062075207Ratregion
5067508AU04770217327429776074297933Ratregion
5069754AU02910912126352924663529367Ratregion
5069770AU02885912625885980358859929Ratregion
5065292BE12139717426113401361134187Ratregion
5062274BE10646418426849729068497474Ratregion
5061080AW53213219025756959557569785Ratregion
5066460AU04834330025710293657103236Ratregion
5066584AU04827117726340346163403638Ratregion
5087219AW52416516325725469957254862Ratregion
5088060Prlr13525929089759291032Ratregion
5088221AU04843918027246975972469939Ratregion
5090727AU04992722825776599157766219Ratregion
5081673BE11797221525750218957502404Ratregion
5089181AU04900316125985060859850769Ratregion
5089261AU04905118125994321459943395Ratregion
5082003BF40902014427170279471702938Ratregion
5503458GDNF_315047625691674556917221Ratregion
5504857ha260088825878094258781904Ratregion
5504480PMC22098P152226093092960931451Ratregion
5506029NM_1942839325941952659419619Ratregion
5501988MARC_21845-21846:1025102921:176525748300657483771Ratregion
5500362GDB:33540916925776772057767887Ratregion
5501460D9S5527025797253357972803Ratregion
5501974MARC_21512-21513:1032982746:3101325724384857244861Ratregion
5502415RH124784027424650474246699Ratregion
Position Markers

Flank 1: (D2Arb7)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2256,660,879 - 56,661,032 (-)MAPPER
Rnor_6.0258,344,100 - 58,344,252NCBI
Rnor_5.0276,649,726 - 76,649,878UniSTS
RGSC_v3.4257,161,998 - 57,162,151RGD
RGSC_v3.4257,161,999 - 57,162,151UniSTS
RGSC_v3.1257,090,231 - 57,090,384RGD
Celera252,279,511 - 52,279,663UniSTS
SHRSP x BN Map225.1898UniSTS
SHRSP x BN Map225.1898RGD
Cytogenetic Map2 RGD
Peak: (D2Mit5)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2266,118,275 - 66,118,463 (+)MAPPER
Rnor_6.0266,828,049 - 66,828,236NCBI
Rnor_5.0286,560,119 - 86,560,306UniSTS
RGSC_v3.4266,680,022 - 66,680,209UniSTS
Celera262,015,680 - 62,015,867UniSTS
RH 3.4 Map2421.0UniSTS
RH 3.4 Map2421.0RGD
RH 2.0 Map2375.6RGD
SHRSP x BN Map229.7698RGD
Flank 2: (D2Rat21)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2274,786,664 - 74,786,777 (+)MAPPER
Rnor_6.0275,687,495 - 75,687,607NCBI
Rnor_5.0295,410,090 - 95,410,202UniSTS
RGSC_v3.4275,806,327 - 75,806,439UniSTS
RGSC_v3.4275,806,326 - 75,806,439RGD
RGSC_v3.1275,734,560 - 75,734,672RGD
Celera270,524,335 - 70,524,442UniSTS
RH 3.4 Map2498.8RGD
RH 3.4 Map2498.8UniSTS
SHRSP x BN Map229.4498UniSTS
SHRSP x BN Map229.4498RGD
FHH x ACI Map234.3399RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21649174061491740Rat
1357990Ael1Aortic elastin QTL 13.10.00091aorta elastin amount (VT:0003905)aortic elastin21907682564076825Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22030467265304672Rat
2300168Bmd47Bone mineral density QTL 476.60.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)22066244865662448Rat
10402051Gdil2Gastrointestinal dilation QTL 2enteric ganglion morphology trait (VT:0001045)length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)22490385374786777Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)22691781781754745Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)22691781781754745Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22691781781754745Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)226917817127469484Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)226917817136917119Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22715716072157160Rat
10755434Coatc7Coat color QTL 70.04794coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23064806575648065Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23502311780023117Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23513484188029593Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)240067944102785628Rat
1300155Bp174Blood pressure QTL 1744.09arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)24280460760653831Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607157142209Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
2293676Bmd19Bone mineral density QTL 1910.70.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)243162366111362592Rat
2293682Bmd24Bone mineral density QTL 248.90.0001femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)243162366111362592Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243162366148478373Rat
631208Bw1Body weight QTL15.09mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)24317101783575226Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
1354592Rf50Renal function QTL 503.5urine output (VT:0003620)timed urine volume (CMO:0000260)25382274774786777Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1579916Bp270Blood pressure QTL 2700.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)25653191259324719Rat
6480225Gdil1Gastrointestinal dilation QTL 1enteric ganglion morphology trait (VT:0001045)length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)25666087974786777Rat
1582246Cm60Cardiac mass QTL 605.8heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)25760561276539510Rat
1558648Smcn1Smooth muscle cell number QTL 10.039blood vessel smooth muscle cell quantity (VT:0010525)aorta smooth muscle cell count per unit vessel length (CMO:0001646)259134147127460910Rat
5684990Bmd82Bone mineral density QTL 822.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)259324377103795077Rat
5684996Bmd85Bone mineral density QTL 854.70.024tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)259324377103795077Rat
61438Cia7Collagen induced arthritis QTL 74.60.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)259324377141596857Rat
631500Bp99Blood pressure QTL 992.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)259324719102755241Rat
1578777Stresp15Stress response QTL 1520.05blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)259846005104846005Rat
2306903Bp336Blood pressure QTL 3360.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)264366971109366971Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
7411551Bw131Body weight QTL 13129.60.001body mass (VT:0001259)body weight gain (CMO:0000420)267942638112942638Rat
1558653Prcr1Prostate cancer resistance QTL 15prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)272532993157142209Rat
1359034Bp274Blood pressure QTL 274arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)27478666494359546Rat
1359034Bp274Blood pressure QTL 274arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)27478666494359546Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross 6480215
qtl_gene more than 30 genes lie in this region 6480215
qtl_general number of animals used: 96 F2 females 6480215
qtl_general software used: MapManager QTXb 6480215
qtl_general measurement method: intestines were stained by acetylcholinesterase (AChE), extent of aganglionosis calculated as ratio of length of the aganglionosis intestine to the length of the entire large intestine 6480215
qtl_general ratio of gross intestine weight (gross intestine weight/body weight) was also calculated 6480215
qtl_statistics LRS:23.9 6480215