GWAS1549420_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1549420_H (Epstein-Barr virus seropositivity QTL GWAS1549420 (human)) Homo sapiens

Symbol: GWAS1549420_H
Name: Epstein-Barr virus seropositivity QTL GWAS1549420 (human)
RGD ID: 597453346
Trait: Epstein-Barr virus seropositivity
Measurement Type: serum anti-Epstein-Barr virus (EBV) antibody level   (CMO:0003143)    
LOD Score: Not Available
P Value: 3.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38632,644,620 - 32,644,621RGD_MAPPER_PIPELINEGRCh38
GRCh37632,612,397 - 32,612,398RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1549420_HHumanserum anti-Epstein-Barr virus (EBV) antibody level  IAGPrs6927022405850206 GWAS_CATALOGPMID:37164013

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1549420_HHumanEpstein-Barr virus seropositivity  IAGPrs6927022405850206 GWAS_CATALOGPMID:37164013
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1351810HLA-DQA1major histocompatibility complex, class II, DQ alpha 163263740632655272Human

Position Markers

Peak: (rs6927022)
Human AssemblyChrPosition (strand)Source
GRCh38632,644,620 - 32,644,621RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358839MULTSCL5_HMultiple sclerosis susceptibility QTL 5 (human)Multiple sclerosis susceptibility61958431145584311Human
597375608GWAS1471682_Hulcerative colitis QTL GWAS1471682 (human)5e-133intestine integrity trait (VT:0010554)63264462032644621Human
597452379GWAS1548453_Hstreptococcus seropositivity QTL GWAS1548453 (human)9e-28streptococcus seropositivity63264462032644621Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
597383408GWAS1479482_HEpstein Barr virus nuclear antigen 1 IgG measurement QTL GWAS1479482 (human)7e-26response to viral infection trait (VT:0010439)63264462032644621Human
1298431RA11_HRheumatoid arthritis QTL 11 (human)0.0000024Joint/bone inflammationrheumatoid arthritis61991188340191709Human
1358854MULTSCL4_HMultiple sclerosis susceptibility QTL 4 (human)Multiple sclerosis susceptibility6691196032911960Human
597383407GWAS1479481_HEpstein Barr virus nuclear antigen 1 IgG measurement QTL GWAS1479481 (human)1e-21response to viral infection trait (VT:0010439)63264462032644621Human
597467462GWAS1563536_Hinflammatory bowel disease QTL GWAS1563536 (human)2e-31intestine integrity trait (VT:0010554)63264462032644621Human
1358857MULTSCL19_HMultiple sclerosis susceptibility QTL 19 (human)Multiple sclerosis susceptibility61958431145584311Human
597438305GWAS1534379_Hulcerative colitis QTL GWAS1534379 (human)5e-65intestine integrity trait (VT:0010554)63264462032644621Human
1643399BMD5_HBone mineral density QTL 5 (human)2.320.0005Bone mineral density6691196032911960Human
597453346GWAS1549420_HEpstein-Barr virus seropositivity QTL GWAS1549420 (human)3e-11Epstein-Barr virus seropositivityserum anti-Epstein-Barr virus (EBV) antibody level (CMO:0003143)63264462032644621Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS1813456_H GCST90006899 Epstein-Barr virus EBNA-1 antibody levels 7,972 White British ancestry individuals A 0.505 2E-76 75.699 rs6927022 0.3 blood immunoglobulin amount (OBA:VT0002460)
 PMID:33204752
GWAS1471682_H GCST001728 Ulcerative colitis Up to 12,924 European ancestry cases, up to 21,442 European ancestry controls A 0.535 5E-133 132.302 rs6927022 1.444 ulcerative colitis (EFO:0000729)
 PMID:23128233
GWAS1479481_H GCST90000522 Anti-Epstein-Barr virus nuclear antigen (EBNA) IgG levels 4,365 Ugandan ancestry individuals A 0.73 1E-21 21 rs6927022 0.26 Epstein Barr virus nuclear antigen 1 IgG measurement (EFO:0007790)
 PMID:32737300
GWAS1479482_H GCST90000522 Anti-Epstein-Barr virus nuclear antigen (EBNA) IgG levels 4,365 Ugandan ancestry individuals A 0.59 7E-26 25.155 rs6927022 0.16 Epstein Barr virus nuclear antigen 1 IgG measurement (EFO:0007790)
 PMID:32737300
None Available GCST005963 Epstein Barr virus nuclear antigen 1 IgG levels 1,473 Ugandan ancestry individuals, 2,162 European ancestry individuals A 0.59 7E-26 25.155 rs6927022 0.16 Epstein Barr virus nuclear antigen 1 IgG measurement (EFO:0007790)
 PMID:29868224
GWAS1534379_H GCST004133 Ulcerative colitis 12,366 European and unknown ancestry cases, 33,609 European and unknown ancestry controls ? NR 5E-65 64.302 rs6927022 N/A ulcerative colitis (EFO:0000729)
 PMID:28067908
GWAS1548453_H GCST90295765 Seropositivity for streptococcus pneumoniae peptide (agilent_231226) 1,745 individuals ? NR 9E-28 27.046 rs6927022 10.924 streptococcus seropositivity (EFO:0803651)
 PMID:37164013
GWAS1549420_H GCST90294403 Seropositivity for human gammaherpesvirus 4 (Epstein-Barr virus) peptide (twist_34377) 1,745 individuals ? NR 3E-11 10.523 rs6927022 6.659 Epstein-Barr virus seropositivity (EFO:0010908)
 PMID:37164013
GWAS1563536_H GCST004131 Inflammatory bowel disease 25,042 European and unknown ancestry cases, 34,915 European and unknown ancestry controls ? NR 2E-31 30.699 rs6927022 N/A inflammatory bowel disease (EFO:0003767)
 PMID:28067908
Database Acc Id Source(s)
GWAS Catalog GCST90294403 GWAS Catalog

RGD Curation Notes
Note Type Note Reference