GWAS1539471_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1539471_H (anti-SARS-CoV-2 IgG measurement, response to COVID-19 vaccine QTL GWAS1539471 (human)) Homo sapiens

Symbol: GWAS1539471_H
Name: anti-SARS-CoV-2 IgG measurement, response to COVID-19 vaccine QTL GWAS1539471 (human)
RGD ID: 597443397
Trait: anti-SARS-CoV-2 IgG measurement, response to COVID-19 vaccine
Measurement Type: blood anti-SARS-CoV-2 antibody level   (CMO:0003966)    
LOD Score: Not Available
P Value: 7.0E-14
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38632,663,679 - 32,663,680RGD_MAPPER_PIPELINEGRCh38
GRCh37632,631,456 - 32,631,457RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1539471_HHumanblood anti-SARS-CoV-2 antibody level  IAGPrs66656759405850206 GWAS_CATALOGPMID:38181733

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1539471_HHumananti-SARS-CoV-2 IgG measurement  IAGPrs66656759405850206 GWAS_CATALOGPMID:38181733
GWAS1539471_HHumanresponse to COVID-19 vaccine  IAGPrs66656759405850206 GWAS_CATALOGPMID:38181733
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1353906HLA-DQB1major histocompatibility complex, class II, DQ beta 163265946732666657Human

Position Markers

Peak: (rs66656759)
Human AssemblyChrPosition (strand)Source
GRCh38632,663,679 - 32,663,680RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358854MULTSCL4_HMultiple sclerosis susceptibility QTL 4 (human)Multiple sclerosis susceptibility6691196032911960Human
1358839MULTSCL5_HMultiple sclerosis susceptibility QTL 5 (human)Multiple sclerosis susceptibility61958431145584311Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
597443397GWAS1539471_Hanti-SARS-CoV-2 IgG measurement, response to COVID-19 vaccine QTL GWAS1539471 (human)7e-14anti-SARS-CoV-2 IgG measurement, response to COVID-19 vaccineblood anti-SARS-CoV-2 antibody level (CMO:0003966)63266367932663680Human
1298431RA11_HRheumatoid arthritis QTL 11 (human)0.0000024Joint/bone inflammationrheumatoid arthritis61991188340191709Human
1358857MULTSCL19_HMultiple sclerosis susceptibility QTL 19 (human)Multiple sclerosis susceptibility61958431145584311Human
1643399BMD5_HBone mineral density QTL 5 (human)2.320.0005Bone mineral density6691196032911960Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS1539471_H GCST90295946 Anti-SARS-CoV-2 spike protein IgG seronegativity after second dose of COVID-19 vaccine 22,272 European ancestry cases, 23,960 European ancestry controls ? NR 7E-14 13.155 rs66656759 1.16 anti-SARS-CoV-2 IgG measurement (EFO:0803358)
response to COVID-19 vaccine (EFO:0803362)
 PMID:38181733
Database Acc Id Source(s)
GWAS Catalog GCST90295946 GWAS Catalog

RGD Curation Notes
Note Type Note Reference