GWAS1391765_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL: GWAS1391765_H (renin measurement, hypertension QTL GWAS1391765 (human)) Homo sapiens

Symbol: GWAS1391765_H
Name: renin measurement, hypertension QTL GWAS1391765 (human)
RGD ID: 597295691
Trait: adrenal gland renin amount   (VT:0010952)    
blood renin amount   (VT:0003349)    
kidney renin amount   (VT:0010559)    
renin activity   (VT:0005581)    
LOD Score: Not Available
P Value: 6.0E-6
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh382224,817,513 - 24,817,514RGD_MAPPER_PIPELINEGRCh38
GRCh372225,213,480 - 25,213,481RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
hypertension  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Hypertension  (IAGP)
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1317805SGSM1small G protein signaling modulator 1222480621124927578Human

Position Markers

Peak: (rs8137145)
Human AssemblyChrPosition (strand)Source
GRCh382224,817,513 - 24,817,514RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581529BP71_HBlood pressure QTL 71 (human)20.001Blood pressurepulse pressure221109496637094966Human
597295691GWAS1391765_Hrenin measurement, hypertension QTL GWAS1391765 (human)0.000006renin activity (VT:0005581)222481751324817514Human
2289428BW313_HBody weight QTL 313 (human)2.090.0015Body weightBMI221134428437344284Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS1391765_H GCST90128470 New onset hypertension (high renin group) 410 Korean ancestry cases, 1,135 Korean ancestry controls ? NR 0.000006 5.222 rs8137145 0.67 renin measurement (EFO:0010616)
hypertension (EFO:0000537)
PMID:35448080
Database Acc Id Source(s)
GWAS Catalog GCST90128470 GWAS Catalog

RGD Curation Notes
Note Type Note Reference