GWAS1391762_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1391762_H (renin measurement, hypertension QTL GWAS1391762 (human)) Homo sapiens

Symbol: GWAS1391762_H
Name: renin measurement, hypertension QTL GWAS1391762 (human)
RGD ID: 597295688
Trait: adrenal gland renin amount   (VT:0010952)    
blood renin amount   (VT:0003349)    
kidney renin amount   (VT:0010559)    
renin activity   (VT:0005581)    
LOD Score: Not Available
P Value: 6.0E-6
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh384108,375,058 - 108,375,059RGD_MAPPER_PIPELINEGRCh38
GRCh374109,296,214 - 109,296,215RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
hypertension  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Hypertension  (IAGP)
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs17038966)
Human AssemblyChrPosition (strand)Source
GRCh384108,375,058 - 108,375,059RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1643256BW127_HBody Weight QTL 127 (human)1.310.007Body weightbody mass index4106319694132319694Human
597295688GWAS1391762_Hrenin measurement, hypertension QTL GWAS1391762 (human)0.000006renin activity (VT:0005581)4108375058108375059Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS1391762_H GCST90128469 New onset hypertension (low renin group) 1,294 Korean ancestry cases, 2,372 Korean ancestry controls ? NR 0.000006 5.222 rs17038966 0.62 renin measurement (EFO:0010616)
hypertension (EFO:0000537)
 PMID:35448080
Database Acc Id Source(s)
GWAS Catalog GCST90128469 GWAS Catalog

RGD Curation Notes
Note Type Note Reference