GWAS1303384_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1303384_H (type 2 diabetes mellitus QTL GWAS1303384 (human)) Homo sapiens

Symbol: GWAS1303384_H
Name: type 2 diabetes mellitus QTL GWAS1303384 (human)
RGD ID: 597207310
Trait: type 2 diabetes mellitus
LOD Score: Not Available
P Value: 3.0E-18
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38922,003,368 - 22,003,369RGD_MAPPER_PIPELINEGRCh38
GRCh37922,003,367 - 22,003,368RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)



References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
2302260CDKN2B-AS1CDKN2B antisense RNA 192199479122128142Human
1348731CDKN2Bcyclin dependent kinase inhibitor 2B92200290322009313Human

Position Markers

Peak: (rs1063192)
Human AssemblyChrPosition (strand)Source
GRCh38922,003,368 - 22,003,369RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
597024693GWAS1120767_Hnasopharyngeal neoplasm QTL GWAS1120767 (human)0.0000008nasopharyngeal neoplasm92200336822003369Human
617258089GWAS2194865_Hschizophrenia, type 2 diabetes mellitus QTL GWAS2194865 (human)1e-16schizophrenia, type 2 diabetes mellitus92200336822003369Human
1357299AASTH47_HAllergic/atopic asthma related QTL 47 (human)0.00028Reversible airflow obstruction9528914931289149Human
628408019GWAS2316248_Hnasopharyngeal neoplasm QTL GWAS2316248 (human)0.0000008nasopharyngeal neoplasm92200336822003369Human
628478162GWAS2386391_Hopen-angle glaucoma QTL GWAS2386391 (human)5e-11eye integrity trait (VT:0011107)92200336822003369Human
406902888GWAS551864_Htype 2 diabetes mellitus QTL GWAS551864 (human)3e-18type 2 diabetes mellitus92200336822003369Human
628477757GWAS2385986_Hoptic disc size trait QTL GWAS2385986 (human)4e-15optic disc size trait92200336822003369Human
597829416GWAS1696807_Htumor necrosis factor ligand superfamily member 14 measurement QTL GWAS1696807 (human)0.000001tumor necrosis factor ligand superfamily member 14 measurement92200336822003369Human
628650836GWAS2559065_Htumor necrosis factor ligand superfamily member 14 measurement QTL GWAS2559065 (human)0.000001cytokine amount (VT:0008713)92200336822003369Human
406901261GWAS550237_Hopen-angle glaucoma QTL GWAS550237 (human)5e-11open-angle glaucoma92200336822003369Human
406900015GWAS548991_Hoptic disc size measurement QTL GWAS548991 (human)4e-15optic disc size measurement92200336822003369Human
1643245BW137_HBody weight QTL 137 (human)2.28Body weight9528914931289149Human
406885813GWAS534789_Hnasopharyngeal neoplasm QTL GWAS534789 (human)0.0000008nasopharyngeal neoplasm92200336822003369Human
2302773MAMTS18_HMammary tumor susceptibility QTL 18 (human)0.039Mammary tumor susceptibility9528914931289149Human
597207310GWAS1303384_Htype 2 diabetes mellitus QTL GWAS1303384 (human)3e-18type 2 diabetes mellitus92200336822003369Human
628476163GWAS2384392_Htype 2 diabetes mellitus QTL GWAS2384392 (human)3e-18type 2 diabetes mellitus92200336822003369Human
2315898GLUCO191_HGlucose level QTL 191 (human)1.83Glucose level9528914931289149Human
628633089GWAS2541318_Hschizophrenia, type 2 diabetes mellitus QTL GWAS2541318 (human)1e-16schizophrenia, type 2 diabetes mellitus92200336822003369Human
2293400PRSTS224_HProstate tumor susceptibility QTL 224 (human)1.62Prostate tumor susceptibility9528914931289149Human
2293433PRSTS223_HProstate tumor susceptibility QTL 223 (human)1.6Prostate tumor susceptibility9528914931289149Human
597980760GWAS1700059_Hoptic disc size trait QTL GWAS1700059 (human)4e-15optic disc size trait92200336822003369Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS2316248_H GCST005113 Nasopharyngeal carcinoma 2,152 Chinese ancestry cases, 3,740 Chinese ancestry controls ? NR 8E-7 6.097 rs1063192 1.1627907 nasopharyngeal neoplasm (EFO:0004252)
 PMID:26545403
GWAS2384392_H GCST006867 Type 2 diabetes 61,714 European ancestry cases, 1,178 Pakistani ancestry cases, 593,952 European ancestry controls, 2,472 Pakistani ancestry controls G 0.440315561394922 3E-18 17.523 rs1063192 0.0634 PMID:30054458
GWAS2385986_H GCST000700 Vertical cup-disc ratio 7,360 European ancestry individuals G 0.46 4E-15 14.398 rs1063192 0.01 optic disc size trait (OBA:VT0006216)
 PMID:20548946
GWAS2386391_H GCST001451 Glaucoma (primary open-angle) 1,394 Japanese ancestry cases, 6,599 Japanese ancestry controls T 0.79 5E-11 10.302 rs1063192 1.33 open-angle glaucoma (EFO:0004190)
 PMID:22419738
GWAS2541318_H GCST90624670 Type 2 diabetes and schyzophrenia 62,892 European ancestry type II diabetes cases, 40,675 European ancestry schizophrenia cases, 661,067 European ancestry controls ? NR 1E-16 16 rs1063192 N/A PMID:36738649
GWAS2559065_H GCST90503396 TNFRSF14 levels 318 European ancestry males ? NR 0.000001 6 rs1063192 4.871 tumor necrosis factor ligand superfamily member 14 measurement (EFO:0010613)
 PMID:38326779
Database Acc Id Source(s)
GWAS Catalog GCST006867 GWAS Catalog

RGD Curation Notes
Note Type Note Reference