GWAS1248821_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS1248821_H (anti-SARS-CoV-2 IgG measurement, response to COVID-19 vaccine QTL GWAS1248821 (human)) Homo sapiens

Symbol: GWAS1248821_H
Name: anti-SARS-CoV-2 IgG measurement, response to COVID-19 vaccine QTL GWAS1248821 (human)
RGD ID: 597152747
Trait: anti-SARS-CoV-2 IgG measurement, response to COVID-19 vaccine
Measurement Type: blood anti-SARS-CoV-2 antibody level   (CMO:0003966)    
LOD Score: Not Available
P Value: 3.0E-6
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3814106,703,184 - 106,703,185RGD_MAPPER_PIPELINEGRCh38
GRCh3714107,159,201 - 107,159,202RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1248821_HHumanblood anti-SARS-CoV-2 antibody level  IAGPrs10137103405850206 GWAS_CATALOGPMID:38181733

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1248821_HHumananti-SARS-CoV-2 IgG measurement  IAGPrs10137103405850206 GWAS_CATALOGPMID:38181733
GWAS1248821_HHumanresponse to COVID-19 vaccine  IAGPrs10137103405850206 GWAS_CATALOGPMID:38181733
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
735342IGHimmunoglobulin heavy locus14105586437106879844Human

Position Markers

Peak: (rs10137103)
Human AssemblyChrPosition (strand)Source
GRCh3814106,703,184 - 106,703,185RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
597152747GWAS1248821_Hanti-SARS-CoV-2 IgG measurement, response to COVID-19 vaccine QTL GWAS1248821 (human)0.000003anti-SARS-CoV-2 IgG measurement, response to COVID-19 vaccineblood anti-SARS-CoV-2 antibody level (CMO:0003966)14106703184106703185Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS1248821_H GCST90295945 Anti-SARS-CoV-2 spike protein IgG seronegativity after first dose of COVID-19 vaccine 37,229 European ancestry cases, 16,837 European ancestry controls G 0.278165 0.000003 5.523 rs10137103 1.07 anti-SARS-CoV-2 IgG measurement (EFO:0803358)
response to COVID-19 vaccine (EFO:0803362)
 PMID:38181733
Database Acc Id Source(s)
GWAS Catalog GCST90295945 GWAS Catalog

RGD Curation Notes
Note Type Note Reference