GWAS1115939_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1115939_H (body mass index QTL GWAS1115939 (human)) Homo sapiens

Symbol: GWAS1115939_H
Name: body mass index QTL GWAS1115939 (human)
RGD ID: 597019865
Trait: body size trait   (VT:0100005)    
Measurement Type: body mass index (BMI)   (CMO:0000105)    
LOD Score: Not Available
P Value: 2.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38915,634,328 - 15,634,329RGD_MAPPER_PIPELINEGRCh38
GRCh37915,634,326 - 15,634,327RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1115939_HHumanbody mass index (BMI)  IAGPrs4740619405850206Based on the EFO term IDGWAS_CATALOGPMID:26426971

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1115939_HHumanbody size trait  IAGPrs4740619405850206Based on the EFO term IDGWAS_CATALOGPMID:26426971

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1115939_HHumanbody mass index  IAGPrs4740619405850206 GWAS_CATALOGPMID:26426971
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Vertebrate Trait

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1348779CCDC171coiled-coil domain containing 17191555288516108926Human

Position Markers

Peak: (rs4740619)
Human AssemblyChrPosition (strand)Source
GRCh38915,634,328 - 15,634,329RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
628671480GWAS2579709_Hbody mass index QTL GWAS2579709 (human)2e-33body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)91563432815634329Human
407143429GWAS792405_Hbody mass index QTL GWAS792405 (human)1e-31body mass index91563432815634329Human
407092423GWAS741399_Hbody mass index QTL GWAS741399 (human)3e-31body mass index91563432815634329Human
597150419GWAS1246493_Hbody mass index QTL GWAS1246493 (human)1e-31body mass index91563432815634329Human
407039940GWAS688916_Hbody mass index QTL GWAS688916 (human)5e-09body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)91563432815634329Human
407042437GWAS691413_Hbody mass index QTL GWAS691413 (human)0.0000009body mass index91563432815634329Human
597227088GWAS1323162_Hbody mass index QTL GWAS1323162 (human)4e-10body mass index91563432815634329Human
597019865GWAS1115939_Hbody mass index QTL GWAS1115939 (human)2e-10body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)91563432815634329Human
597074650GWAS1170724_Hbody mass index QTL GWAS1170724 (human)3e-10body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)91563432815634329Human
407081230GWAS730206_Hbody mass index QTL GWAS730206 (human)3e-10body mass index91563432815634329Human
597091330GWAS1187404_Hbody mass index QTL GWAS1187404 (human)6e-09body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)91563432815634329Human
2302773MAMTS18_HMammary tumor susceptibility QTL 18 (human)0.039Mammary tumor susceptibility9528914931289149Human
2315898GLUCO191_HGlucose level QTL 191 (human)1.83Glucose level9528914931289149Human
2293433PRSTS223_HProstate tumor susceptibility QTL 223 (human)1.6Prostate tumor susceptibility9528914931289149Human
407007641GWAS656617_Hbody mass index QTL GWAS656617 (human)4e-10body mass index91563432815634329Human
407065944GWAS714920_Hbody mass index QTL GWAS714920 (human)2e-33body mass index91563432815634329Human
597190981GWAS1287055_Hbody mass index QTL GWAS1287055 (human)2e-33body mass index91563432815634329Human
597049416GWAS1145490_Hmetabolic syndrome QTL GWAS1145490 (human)3e-19metabolic syndrome91563432815634329Human
596954955GWAS1074474_Hmetabolic syndrome QTL GWAS1074474 (human)3e-19metabolic syndrome91563432815634329Human
628447082GWAS2355311_Hbody mass index QTL GWAS2355311 (human)4e-10body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)91563432815634329Human
628375446GWAS2295670_Hbody mass index QTL GWAS2295670 (human)3e-31body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)91563432815634329Human
628857695GWAS2765924_Hbody mass index QTL GWAS2765924 (human)1e-31body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)91563432815634329Human
1357299AASTH47_HAllergic/atopic asthma related QTL 47 (human)0.00028Reversible airflow obstruction9528914931289149Human
597019005GWAS1115079_Hbody mass index QTL GWAS1115079 (human)0.0000009body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)91563432815634329Human
596955261GWAS1074780_Hbody mass index QTL GWAS1074780 (human)3e-27body mass index91563432815634329Human
628575111GWAS2483340_Hbody mass index QTL GWAS2483340 (human)3e-27body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)91563432815634329Human
597292904GWAS1388978_Hbody mass index QTL GWAS1388978 (human)3e-27body mass index91563432815634329Human
628439942GWAS2348171_Hmetabolic syndrome QTL GWAS2348171 (human)3e-19metabolic syndrome91563432815634329Human
1643245BW137_HBody weight QTL 137 (human)2.28Body weight9528914931289149Human
407039220GWAS688196_Hbody mass index QTL GWAS688196 (human)6e-09body mass index91563432815634329Human
597036640GWAS1132714_Hbody mass index QTL GWAS1132714 (human)3e-31body mass index91563432815634329Human
2293400PRSTS224_HProstate tumor susceptibility QTL 224 (human)1.62Prostate tumor susceptibility9528914931289149Human
406891198GWAS540174_Hbody mass index QTL GWAS540174 (human)2e-10body mass index91563432815634329Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS1115079_H GCST002783 Body mass index up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals T 0.54 9E-7 6.046 rs4740619 0.02 body mass index (EFO:0004340)
 PMID:25673413
GWAS1115939_H GCST005951 Body mass index up to 309,889 European ancestry individuals T 0.545371365417758 2E-10 9.699 rs4740619 0.017116887 body mass index (EFO:0004340)
 PMID:26426971
GWAS2295670_H GCST009001 Body mass index 374,756 European ancestry male individuals T 0.5436 3E-31 30.523 rs4740619 0.0189 body mass index (EFO:0004340)
 PMID:30239722
GWAS2348171_H GCST90444487 Metabolic syndrome 1,384,348 European ancestry individuals ? NR 3E-19 18.523 rs4740619 0.0120262 metabolic syndrome (EFO:0000195)
 PMID:39349817
GWAS2355311_H GCST006368 Body mass index 315,347 European ancestry individuals, 8,322 Hispanic/Latino individuals, 7,290 East Asian ancestry individuals, 3,069 African American individuals, 459 South Asian ancestry individuals T NR 4E-10 9.398 rs4740619 0.016 body mass index (EFO:0004340)
 PMID:30108127
GWAS1170724_H GCST004904 Body mass index up to 72,390 Japanese ancestry women, up to 85,894 Japanese ancestry men C 0.48 3E-10 9.523 rs4740619 0.016 body mass index (EFO:0004340)
 PMID:28892062
GWAS688916_H GCST002783 Body mass index up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals T 0.542 5E-9 8.302 rs4740619 0.018 body mass index (EFO:0004340)
 PMID:25673413
GWAS1187404_H GCST002783 Body mass index up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals T 0.54 6E-9 8.222 rs4740619 0.017 body mass index (EFO:0004340)
 PMID:25673413
None Available GCST009004 Body mass index 806,834 European ancestry individuals T 0.5436 3E-31 30.523 rs4740619 0.0189 body mass index (EFO:0004340)
 PMID:30239722
None Available GCST009003 Body mass index 434,794 European ancestry female individuals T 0.5436 3E-31 30.523 rs4740619 0.0189 body mass index (EFO:0004340)
 PMID:30239722
GWAS2483340_H GCST90446645 Body mass index 650,000 European ancestry individuals T 0.5435 3E-27 26.523 rs4740619 0.0188 body mass index (EFO:0004340)
 PMID:39375568
GWAS2579709_H GCST90255621 Body mass index 1,122,049 European ancestry individuals C NR 2E-33 32.699 rs4740619 0.0176 body mass index (EFO:0004340)
 PMID:36581621
GWAS2765924_H GCST90179150 Body mass index (MTAG) 694,649 European ancestry individuals T NR 1E-31 31 rs4740619 0.018792 body mass index (EFO:0004340)
 PMID:36376304
Database Acc Id Source(s)
GWAS Catalog GCST005951 GWAS Catalog

RGD Curation Notes
Note Type Note Reference