GWAS1082678_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1082678_H (type 2 diabetes mellitus, coronary artery disease QTL GWAS1082678 (human)) Homo sapiens

Symbol: GWAS1082678_H
Name: type 2 diabetes mellitus, coronary artery disease QTL GWAS1082678 (human)
RGD ID: 596963159
Trait: type 2 diabetes mellitus, coronary artery disease
LOD Score: Not Available
P Value: 8.0E-25
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38922,133,774 - 22,133,775RGD_MAPPER_PIPELINEGRCh38
GRCh37922,133,773 - 22,133,774RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)



References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs76011118)
Human AssemblyChrPosition (strand)Source
GRCh38922,133,774 - 22,133,775RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
596963159GWAS1082678_Htype 2 diabetes mellitus, coronary artery disease QTL GWAS1082678 (human)8e-25type 2 diabetes mellitus, coronary artery disease92213377422133775Human
597392536GWAS1488610_Htype 2 diabetes mellitus QTL GWAS1488610 (human)0.0000001type 2 diabetes mellitus92213377422133775Human
1357299AASTH47_HAllergic/atopic asthma related QTL 47 (human)0.00028Reversible airflow obstruction9528914931289149Human
596963263GWAS1082782_Htype 2 diabetes mellitus, coronary artery disease QTL GWAS1082782 (human)6e-25type 2 diabetes mellitus, coronary artery disease92213377422133775Human
628830292GWAS2738521_Htype 2 diabetes mellitus, coronary artery disease QTL GWAS2738521 (human)8e-25coronary artery integrity trait (VT:0010746)92213377422133775Human
628829771GWAS2738000_Htype 2 diabetes mellitus, coronary artery disease QTL GWAS2738000 (human)6e-25coronary artery integrity trait (VT:0010746)92213377422133775Human
628416485GWAS2324714_Htype 2 diabetes mellitus QTL GWAS2324714 (human)0.0000001type 2 diabetes mellitus92213377422133775Human
1643245BW137_HBody weight QTL 137 (human)2.28Body weight9528914931289149Human
597456393GWAS1552467_Htype 2 diabetes mellitus, coronary artery disease QTL GWAS1552467 (human)6e-25type 2 diabetes mellitus, coronary artery disease92213377422133775Human
2302773MAMTS18_HMammary tumor susceptibility QTL 18 (human)0.039Mammary tumor susceptibility9528914931289149Human
2315898GLUCO191_HGlucose level QTL 191 (human)1.83Glucose level9528914931289149Human
597455749GWAS1551823_Htype 2 diabetes mellitus, coronary artery disease QTL GWAS1551823 (human)8e-25type 2 diabetes mellitus, coronary artery disease92213377422133775Human
2293400PRSTS224_HProstate tumor susceptibility QTL 224 (human)1.62Prostate tumor susceptibility9528914931289149Human
407062169GWAS711145_Htype 2 diabetes mellitus QTL GWAS711145 (human)0.0000001type 2 diabetes mellitus92213377422133775Human
2293433PRSTS223_HProstate tumor susceptibility QTL 223 (human)1.6Prostate tumor susceptibility9528914931289149Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS2324714_H GCST009379 Type 2 diabetes 74,124 European ancestry cases, 824,006 European ancestry controls A 0.0341 1E-7 7 rs76011118 1.11 PMID:30297969
GWAS2738000_H GCST90451699 Type 2 diabetes mellitus adjusted for BMI or coronary artery disease (pleiotropy) 50,409 European ancestry type 2 diabetes adjusted for BMI cases, 181,522 European ancestry coronary artery disease cases, 1,508,065 European ancestry controls ? NR 6E-25 24.222 rs76011118 N/A coronary artery disease (EFO:0001645)
 PMID:38062574
GWAS2738521_H GCST90451698 Type 2 diabetes mellitus or coronary artery disease (pleiotropy) 74,124 European ancestry type 2 diabetes cases, 181,522 European ancestry coronary artery disease cases, 1,808,174 European ancestry controls ? NR 8E-25 24.097 rs76011118 N/A coronary artery disease (EFO:0001645)
 PMID:38062574
Database Acc Id Source(s)
GWAS Catalog GCST90451698 GWAS Catalog

RGD Curation Notes
Note Type Note Reference