GWAS961884_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS961884_H (serum non-albumin protein measurement QTL GWAS961884 (human)) Homo sapiens

Symbol: GWAS961884_H
Name: serum non-albumin protein measurement QTL GWAS961884 (human)
RGD ID: 407312908
Trait: serum non-albumin protein measurement
Measurement Type: serum globulin level   (CMO:0002399)    
LOD Score: Not Available
P Value: 2.0E-19
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38106,107,074 - 6,107,075RGD_MAPPER_PIPELINEGRCh38
GRCh37106,149,037 - 6,149,038RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS961884_HHumanserum globulin level  IAGPrs12778662405850206Based on the EFO term IDGWAS_CATALOGPMID:33462484

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS961884_HHumanserum non-albumin protein measurement  IAGPrs12778662405850206 GWAS_CATALOGPMID:33462484
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1322546RBM17RNA binding motif protein 171060890346117447Human

Position Markers

Peak: (rs12778662)
Human AssemblyChrPosition (strand)Source
GRCh38106,107,074 - 6,107,075RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407010528GWAS659504_Hsoluble interleukin-2 receptor subunit alpha measurement, gestational serum measurement, protein measurement, parental genotype effect measurement QTL GWAS659504 (human)4e-09soluble interleukin-2 receptor subunit alpha measurement, gestational serum measurement, protein measurement, parental genotype effect measurement1061070746107075Human
407174416GWAS823392_Hblood protein measurement QTL GWAS823392 (human)3e-1114blood protein measurementblood protein measurement (CMO:0000028)1061070746107075Human
407174414GWAS823390_Hblood protein measurement QTL GWAS823390 (human)5e-1311blood protein measurementblood protein measurement (CMO:0000028)1061070746107075Human
407312908GWAS961884_Hserum non-albumin protein measurement QTL GWAS961884 (human)2e-19serum non-albumin protein measurementserum globulin level (CMO:0002399)1061070746107075Human
407067471GWAS716447_Hblood protein measurement QTL GWAS716447 (human)1e-14blood protein measurementblood protein measurement (CMO:0000028)1061070746107075Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS659504_H GCST006621 Midgestational cytokine/chemokine levels (maternal genetic effect) 790 Hispanic, European, Asian, South Asian or African American individuals T 0.07 4E-9 8.398 rs12778662 0.65 soluble interleukin-2 receptor subunit alpha measurement (EFO:0007650)
gestational serum measurement (EFO:0007964)
protein measurement (EFO:0004747)
parental genotype effect measurement (EFO:0005939)
 PMID:30134952
GWAS716447_H GCST90019522 Serum total protein levels 313,032 European ancestry individuals, 5,573 African ancestry individuals, 6,687 South Asian ancestry individuals T NR 1E-14 14 rs12778662 0.0349 blood protein measurement (EFO:0007937)
 PMID:33462484
GWAS823390_H GCST90315162 IL2RA/TNFRSF4 protein level ratio 43,509 European ancestry individuals ? NR 5E-1311 1310.302 rs12778662 0.932267 blood protein measurement (EFO:0007937)
 PMID:38412862
GWAS823392_H GCST90315163 IL2RA/TNFRSF8 protein level ratio 43,509 European ancestry individuals ? NR 3E-1114 1113.523 rs12778662 0.857706 blood protein measurement (EFO:0007937)
 PMID:38412862
GWAS961884_H GCST90019515 Non-albumin protein levels 313,032 European ancestry individuals, 5,573 African ancestry individuals, 6,687 South Asian ancestry individuals T NR 2E-19 18.699 rs12778662 0.0407 serum non-albumin protein measurement (EFO:0004568)
 PMID:33462484
Database Acc Id Source(s)
GWAS Catalog GCST90019515 GWAS Catalog

RGD Curation Notes
Note Type Note Reference