GWAS950136_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS950136_H (pelvic organ prolapse QTL GWAS950136 (human)) Homo sapiens

Symbol: GWAS950136_H
Name: pelvic organ prolapse QTL GWAS950136 (human)
RGD ID: 407301160
Trait: pelvic organ prolapse
LOD Score: Not Available
P Value: 4.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381573,933,047 - 73,933,048RGD_MAPPER_PIPELINEGRCh38
GRCh371574,225,388 - 74,225,389RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1318705LOXL1lysyl oxidase like 1157392646273952136Human
126928168LOC121530591Sharpr-MPRA regulatory region 13651157393282873933122Human

Position Markers

Peak: (rs4886778)
Human AssemblyChrPosition (strand)Source
GRCh381573,933,047 - 73,933,048RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406945605GWAS594581_HBMI-adjusted waist-hip ratio QTL GWAS594581 (human)9e-10BMI-adjusted waist-hip ratio157393304773933048Human
406929994GWAS578970_Hbrain volume measurement QTL GWAS578970 (human)2e-09brain volume measurementbrain morphological measurement (CMO:0000136)157393304773933048Human
406996463GWAS645439_HBMI-adjusted waist circumference QTL GWAS645439 (human)1e-26BMI-adjusted waist circumference157393304773933048Human
407301160GWAS950136_Hpelvic organ prolapse QTL GWAS950136 (human)4e-08pelvic organ prolapse157393304773933048Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS578970_H GCST009518 Brain region volumes 19,629 British ancestry individuals ? NR 2E-9 8.699 rs4886778 N/A brain volume measurement (EFO:0006930)
 PMID:31676860
GWAS594581_H GCST009858 Waist-to-hip ratio adjusted for BMI 457,690 European ancestry individuals ? NR 9E-10 9.046 rs4886778 N/A BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:31669095
GWAS645439_H GCST009867 Waist circumference adjusted for body mass index 457,690 European ancestry individuals ? NR 1E-26 26 rs4886778 N/A BMI-adjusted waist circumference (EFO:0007789)
 PMID:31669095
GWAS950136_H GCST90102470 Pelvic organ prolapse 28,086 European ancestry cases, 546,291 European ancestry controls A 0.46 4E-8 7.398 rs4886778 1.05 pelvic organ prolapse (EFO:0004710)
 PMID:35739095
Database Acc Id Source(s)
GWAS Catalog GCST90102470 GWAS Catalog

RGD Curation Notes
Note Type Note Reference