GWAS900881_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS900881_H (alkaline phosphatase measurement QTL GWAS900881 (human)) Homo sapiens

Symbol: GWAS900881_H
Name: alkaline phosphatase measurement QTL GWAS900881 (human)
RGD ID: 407251905
Trait: alkaline phosphatase measurement
Measurement Type: blood alkaline phosphatase activity level   (CMO:0000576)    
LOD Score: Not Available
P Value: 3.0E-13
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38119,238,019 - 19,238,020RGD_MAPPER_PIPELINEGRCh38
GRCh37119,564,513 - 19,564,514RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS900881_HHumanblood alkaline phosphatase activity level  IAGPrs144713581405850206Based on the EFO term IDGWAS_CATALOGPMID:34594039

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS900881_HHumanalkaline phosphatase measurement  IAGPrs144713581405850206 GWAS_CATALOGPMID:34594039
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
13793352EMC1-AS1EMC1 antisense RNA 111921038619240704Human
1602125EMC1ER membrane protein complex subunit 111921566019251524Human

Position Markers

Peak: (rs144713581)
Human AssemblyChrPosition (strand)Source
GRCh38119,238,019 - 19,238,020RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
407251905GWAS900881_Halkaline phosphatase measurement QTL GWAS900881 (human)3e-13alkaline phosphatase measurementblood alkaline phosphatase activity level (CMO:0000576)11923801919238020Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS900881_H GCST90018942 Serum alkaline phosphatase levels 344,292 European ancestry individuals, 118,886 East Asian ancestry individuals A NR 3E-13 12.523 rs144713581 0.8951 alkaline phosphatase measurement (EFO:0004533)
 PMID:34594039
Database Acc Id Source(s)
GWAS Catalog GCST90018942 GWAS Catalog

RGD Curation Notes
Note Type Note Reference