GWAS890297_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS890297_H (body fat percentage QTL GWAS890297 (human)) Homo sapiens

Symbol: GWAS890297_H
Name: body fat percentage QTL GWAS890297 (human)
RGD ID: 407241321
Trait: body fat percentage
Measurement Type: body fat percentage   (CMO:0000302)    
LOD Score: Not Available
P Value: 4.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3818,422,018 - 8,422,019RGD_MAPPER_PIPELINEGRCh38
GRCh3718,482,078 - 8,482,079RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS890297_HHumanbody fat percentage  IAGPrs301806405850206Based on the EFO term IDGWAS_CATALOGPMID:37867527

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS890297_HHumanbody fat percentage  IAGPrs301806405850206 GWAS_CATALOGPMID:37867527
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1344336REREarginine-glutamic acid dipeptide repeats183524048817640Human

Position Markers

Peak: (rs301806)
Human AssemblyChrPosition (strand)Source
GRCh3818,422,018 - 8,422,019RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
406921922GWAS570898_Hirritable bowel syndrome QTL GWAS570898 (human)2e-09unipolar depression184220188422019Human
407108837GWAS757813_HEczematoid dermatitis, allergic rhinitis QTL GWAS757813 (human)1e-12Eczematoid dermatitis, allergic rhinitis184220188422019Human
407211651GWAS860627_HEczematoid dermatitis QTL GWAS860627 (human)1e-16Eczematoid dermatitis184220188422019Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
407078061GWAS727037_Hwaist-hip ratio QTL GWAS727037 (human)0.000001waist-hip ratiowaist to hip ratio (WHR) (CMO:0000020)184220188422019Human
407241321GWAS890297_Hbody fat percentage QTL GWAS890297 (human)4e-11body fat percentagebody fat percentage (CMO:0000302)184220188422019Human
407228917GWAS877893_Hallergic disease QTL GWAS877893 (human)2e-20allergic disease184220188422019Human
406948433GWAS597409_Hneurotic disorder QTL GWAS597409 (human)0.000004neurotic disorder184220188422019Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
406973365GWAS622341_Hsmoking initiation QTL GWAS622341 (human)5e-33smoking initiation184220188422019Human
407071924GWAS720900_Hsystemic lupus erythematosus QTL GWAS720900 (human)8e-09systemic lupus erythematosus184220188422019Human
406990233GWAS639209_Hwellbeing measurement QTL GWAS639209 (human)2e-12wellbeing measurement184220188422019Human
406886172GWAS535148_Hdepressive symptom measurement QTL GWAS535148 (human)1e-09depressive symptom measurement184220188422019Human
407058399GWAS707375_Hchronotype measurement QTL GWAS707375 (human)5e-08chronotype measurement184220188422019Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS535148_H GCST005323 Depressive symptoms (MTAG) 354,862 European ancestry individuals C 0.4406 1E-9 9 rs301806 0.0131 depressive symptom measurement (EFO:0007006)
 PMID:29292387
GWAS570898_H GCST90277988 Irritable bowel syndrome (MTAG) 887,490 European ancestry individuals (MTAG effective sample size boosted by neuroticism, depression and anxiety samples) T NR 2E-9 8.699 rs301806 0.009 irritable bowel syndrome (EFO:0000555)
 PMID:37085903
GWAS597409_H GCST010017 Neuroticism 274,107 British ancestry individuals C NR 0.000004 5.398 rs301806 1.009 neurotic disorder (EFO:0004257)
 PMID:32231276
GWAS622341_H GCST90243985 Smoking initiation 3,382,012 European ancestry, East Asian ancestry, Hispanic or Latin American, African ancestry individuals T 0.594 5E-33 32.302 rs301806 0.00921 smoking initiation (EFO:0005670)
 PMID:36477530
GWAS639209_H GCST007341 Well-being spectrum (multivariate analysis) 2,083,151 European ancestry individuals T 0.565850667271711 2E-12 11.699 rs301806 0.006497706 wellbeing measurement (EFO:0007869)
 PMID:30643256
GWAS707375_H GCST007986 Ease of getting up in the morning 385,949 European ancestry individuals C 0.4208 5E-8 7.302 rs301806 0.0095 chronotype measurement (EFO:0008328)
 PMID:30804565
None Available GCST90309337 Depressive symptomatology (confirmatory factor analysis Factor 2) 117,684 European ancestry individuals ? NR 4E-8 7.398 rs301806 N/A depressive symptom measurement (EFO:0007006)
 PMID:38965376
GWAS720900_H GCST90270940 Systemic lupus erythematosus (MTAG) at least 5,877 East Asian ancestry cases, at least 188,588 East Asian ancestry controls, at least 14,355 European ancestry cases, at least 505,956 European ancestry controls, at least 1,393 admixed American ancestry cases, at least 2,327 admixed American ancestry controls (MTAG boosted by autoimmune diseases samples) C NR 8E-9 8.097 rs301806 0.044 PMID:36750564
GWAS727037_H GCST008998 Waist-hip ratio 316,772 European ancestry male individuals T 0.5925 0.000001 6 rs301806 0.0087 waist-hip ratio (EFO:0004343)
 PMID:30239722
GWAS757813_H GCST009717 Hay fever and/or eczema 84,034 European ancestry cases, 239,773 European ancestry controls T 0.5842 1E-12 12 rs301806 1.0439503 Eczematoid dermatitis (HP:0000964)
allergic rhinitis (EFO:0005854)
 PMID:31361310
GWAS860627_H GCST007075 Eczema approximately 459,000 European ancestry individuals ? NR 1E-16 16 rs301806 N/A Eczematoid dermatitis (HP:0000964)
 PMID:30595370
GWAS877893_H GCST005038 Allergic disease (asthma, hay fever or eczema) 180,129 European ancestry cases, 180,709 European ancestry controls T 0.54 2E-20 19.699 rs301806 1.048 PMID:29083406
GWAS890297_H GCST90432179 Body fat percentage (adjusted for testosterone and SHBG) 157,937 British ancestry males ? NR 4E-11 10.398 rs301806 0.12 body fat percentage (EFO:0007800)
 PMID:37867527
None Available GCST006041 Major depressive disorder 84,847 European ancestry cases, 241,266 European ancestry controls T 0.551911 2E-9 8.699 rs301806 0.0271 PMID:27479909
Database Acc Id Source(s)
GWAS Catalog GCST90432179 GWAS Catalog

RGD Curation Notes
Note Type Note Reference