GWAS875385_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS875385_H (QRS complex, QRS duration QTL GWAS875385 (human)) Homo sapiens

Symbol: GWAS875385_H
Name: QRS complex, QRS duration QTL GWAS875385 (human)
RGD ID: 407226409
Trait: QRS complex, QRS duration
Measurement Type: QRS duration   (CMO:0000267)    
LOD Score: Not Available
P Value: 5.0E-13
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3812114,943,935 - 114,943,936RGD_MAPPER_PIPELINEGRCh38
GRCh3712115,381,740 - 115,381,741RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS875385_HHumanQRS duration  IAGPrs10850409405850206Based on the EFO term IDGWAS_CATALOGPMID:27659466

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS875385_HHumanQRS complex  IAGPrs10850409405850206 GWAS_CATALOGPMID:27659466
GWAS875385_HHumanQRS duration  IAGPrs10850409405850206 GWAS_CATALOGPMID:27659466
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement
QRS duration  (IAGP)

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs10850409)
Human AssemblyChrPosition (strand)Source
GRCh3812114,943,935 - 114,943,936RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407227781GWAS876757_HPR segment QTL GWAS876757 (human)8e-13PR segmentPR interval (CMO:0000233)12114943935114943936Human
1559125SPSL2_HSerum P-selectin level QTL 2 (human)2.59Serum P-selectin level1289897665115897665Human
1298449UAE2_HUrinary albumin excretion QTL 2 (human)20.005Urinary albumin excretionurine albumin:creatinine ratio (ACR)12102836889128836889Human
407226407GWAS875383_HQRS amplitude, QRS complex QTL GWAS875383 (human)1e-17QRS amplitude, QRS complexQRS amplitude (CMO:0000268)12114943935114943936Human
1643258BW205_HBody weight QTL 205 (human)4.080.00001Body fat amountpercent body fat1296630114122630114Human
1643452BW104_HBody weight QTL 104 (human)1.890.005Body fat amountabdominal visceral12102395874128395874Human
1357361BW37_HBody weight QTL 37 (human)4.080.00001Body fat amount12102836889116423339Human
407227392GWAS876368_HQRS amplitude, QRS complex QTL GWAS876368 (human)0.0000001QRS amplitude, QRS complexQRS amplitude (CMO:0000268)12114943935114943936Human
407227726GWAS876702_HQRS amplitude, QRS complex QTL GWAS876702 (human)6e-17QRS amplitude, QRS complexQRS amplitude (CMO:0000268)12114943935114943936Human
407226409GWAS875385_HQRS complex, QRS duration QTL GWAS875385 (human)5e-13QRS complex, QRS durationQRS duration (CMO:0000267)12114943935114943936Human
1643264BW195_HBody weight QTL 195 (human)0.0151Body weightBMI1289897665115897665Human
1357387BW58_HBody weight QTL 58 (human)2.30.0001Body weightfat free mass after exercise training1289438856115438856Human
1358827MULTSCL22_HMultiple sclerosis susceptibility QTL 22 (human)Multiple sclerosis susceptibility1289897665115897665Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS875383_H GCST003872 QRS complex (12-leadsum) up to 47,942 European ancestry individuals, up to 690 Orcadian (founder/genetic isolate) individuals ? NR 1E-17 17 rs10850409 N/A QRS amplitude (EFO:0007742)
QRS complex (EFO:0005054)
 PMID:27659466
GWAS875385_H GCST003844 QRS duration 59,565 European ancestry individuals, 690 Orcadian (founder/genetic isolate) individuals ? NR 5E-13 12.302 rs10850409 N/A QRS complex (EFO:0005054)
QRS duration (EFO:0005055)
 PMID:27659466
GWAS876368_H GCST003871 QRS complex (Cornell) up to 58,172 European ancestry individuals, up to 690 Orcadian (founder/genetic isolate) individuals ? NR 1E-7 7 rs10850409 N/A QRS amplitude (EFO:0007742)
QRS complex (EFO:0005054)
 PMID:27659466
GWAS876702_H GCST003870 QRS complex (Sokolow-Lyon) up to 54,303 European ancestry individuals, up to 690 Orcadian (founder/genetic isolate) individuals ? NR 6E-17 16.222 rs10850409 N/A QRS amplitude (EFO:0007742)
QRS complex (EFO:0005054)
 PMID:27659466
GWAS876757_H GCST002456 PR segment duration 16,468 European ancestry individuals A 0.273 8E-13 12.097 rs10850409 1.651 PR segment (EFO:0005095)
 PMID:24850809
Database Acc Id Source(s)
GWAS Catalog GCST003844 GWAS Catalog

RGD Curation Notes
Note Type Note Reference