GWAS827625_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS827625_H (vital capacity QTL GWAS827625 (human)) Homo sapiens

Symbol: GWAS827625_H
Name: vital capacity QTL GWAS827625 (human)
RGD ID: 407178649
Trait: vital capacity
LOD Score: Not Available
P Value: 4.0E-23
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38116,975,285 - 16,975,286RGD_MAPPER_PIPELINEGRCh38
GRCh37117,301,780 - 17,301,781RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS827625_HHumanvital capacity  IAGPrs761422405850206 GWAS_CATALOGPMID:30595370
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1314413MFAP2microfibril associated protein 211697450216981583Human

Position Markers

Peak: (rs761422)
Human AssemblyChrPosition (strand)Source
GRCh38116,975,285 - 16,975,286RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
407220903GWAS869879_HBMI-adjusted hip circumference QTL GWAS869879 (human)5e-15BMI-adjusted hip circumferencehip circumference (CMO:0000014)11697528516975286Human
407261453GWAS910429_HAbdominal Aortic Aneurysm QTL GWAS910429 (human)2e-08Abdominal Aortic Aneurysm11697528516975286Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
407178649GWAS827625_Hvital capacity QTL GWAS827625 (human)4e-23vital capacity11697528516975286Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS827625_H GCST007081 Lung function (FVC) approximately 372,000 European ancestry individuals ? NR 4E-23 22.398 rs761422 N/A vital capacity (EFO:0004312)
 PMID:30595370
GWAS869879_H GCST90020028 Hip circumference adjusted for BMI 219,872 British ancestry women G NR 5E-15 14.302 rs761422 0.0219307 BMI-adjusted hip circumference (EFO:0008039)
 PMID:34021172
GWAS910429_H GCST90432152 Abdominal aortic aneurysm 37,214 European ancestry cases, 997,776 European ancestry controls, 2,007 African ancestry cases, 88,331 African ancestry controls ? NR 2E-8 7.699 rs761422 0.0451 Abdominal Aortic Aneurysm (EFO:0004214)
 PMID:37845353
Database Acc Id Source(s)
GWAS Catalog GCST007081 GWAS Catalog

RGD Curation Notes
Note Type Note Reference