GWAS822023_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS822023_H (alkaline phosphatase measurement QTL GWAS822023 (human)) Homo sapiens

Symbol: GWAS822023_H
Name: alkaline phosphatase measurement QTL GWAS822023 (human)
RGD ID: 407173047
Trait: alkaline phosphatase measurement
Measurement Type: blood alkaline phosphatase activity level   (CMO:0000576)    
LOD Score: Not Available
P Value: 1.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38120,689,814 - 20,689,815RGD_MAPPER_PIPELINEGRCh38
GRCh37121,016,307 - 21,016,308RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS822023_HHumanblood alkaline phosphatase activity level  IAGPrs67017818405850206Based on the EFO term IDGWAS_CATALOGPMID:33462484

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS822023_HHumanalkaline phosphatase measurement  IAGPrs67017818405850206 GWAS_CATALOGPMID:33462484
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1344438KIF17kinesin family member 1712066163020718007Human

Position Markers

Peak: (rs67017818)
Human AssemblyChrPosition (strand)Source
GRCh38120,689,814 - 20,689,815RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
407173047GWAS822023_Halkaline phosphatase measurement QTL GWAS822023 (human)1e-11alkaline phosphatase measurementblood alkaline phosphatase activity level (CMO:0000576)12068981420689815Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS822023_H GCST90019494 Serum alkaline phosphatase levels 342,535 European ancestry individuals, 6,019 African ancestry individuals, 7,337 South Asian ancestry individuals G NR 1E-11 11 rs67017818 0.0225 alkaline phosphatase measurement (EFO:0004533)
 PMID:33462484
Database Acc Id Source(s)
GWAS Catalog GCST90019494 GWAS Catalog

RGD Curation Notes
Note Type Note Reference