GWAS811354_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS811354_H (CD8-positive T-lymphocyte count QTL GWAS811354 (human)) Homo sapiens

Symbol: GWAS811354_H
Name: CD8-positive T-lymphocyte count QTL GWAS811354 (human)
RGD ID: 407162378
Trait: CD8-positive T-lymphocyte count
Measurement Type: blood CD8 cell count   (CMO:0000597)    
LOD Score: Not Available
P Value: 6.0E-21
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38631,284,619 - 31,284,620RGD_MAPPER_PIPELINEGRCh38
GRCh37631,252,396 - 31,252,397RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS811354_HHumanblood CD8 cell count  IAGPrs2524054405850206Based on the EFO term IDGWAS_CATALOGPMID:20045101

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS811354_HHumanCD8-positive T-lymphocyte count  IAGPrs2524054405850206 GWAS_CATALOGPMID:20045101
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs2524054)
Human AssemblyChrPosition (strand)Source
GRCh38631,284,619 - 31,284,620RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358854MULTSCL4_HMultiple sclerosis susceptibility QTL 4 (human)Multiple sclerosis susceptibility6691196032911960Human
1358839MULTSCL5_HMultiple sclerosis susceptibility QTL 5 (human)Multiple sclerosis susceptibility61958431145584311Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
1298431RA11_HRheumatoid arthritis QTL 11 (human)0.0000024Joint/bone inflammationrheumatoid arthritis61991188340191709Human
1358857MULTSCL19_HMultiple sclerosis susceptibility QTL 19 (human)Multiple sclerosis susceptibility61958431145584311Human
407162377GWAS811353_HCD4:CD8 lymphocyte ratio QTL GWAS811353 (human)2e-28CD4:CD8 lymphocyte ratioblood CD4 cell count to CD8 cell count ratio (CMO:0000598)63128461931284620Human
1643399BMD5_HBone mineral density QTL 5 (human)2.320.0005Bone mineral density6691196032911960Human
407162378GWAS811354_HCD8-positive T-lymphocyte count QTL GWAS811354 (human)6e-21CD8-positive T-lymphocyte countblood CD8 cell count (CMO:0000597)63128461931284620Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS811353_H GCST000553 CD4:CD8 lymphocyte ratio 2,538 European ancestry twins from 1,089 families A 0.32 2E-28 27.699 rs2524054 0.37 CD4:CD8 lymphocyte ratio (EFO:0004839)
 PMID:20045101
GWAS811354_H GCST008638 CD8-positive T-lymphocyte count 2,538 European ancestry twins from 1,089 families A 0.32 6E-21 20.222 rs2524054 0.37 CD8-positive T-lymphocyte count (EFO:0010107)
 PMID:20045101
Database Acc Id Source(s)
GWAS Catalog GCST008638 GWAS Catalog

RGD Curation Notes
Note Type Note Reference