GWAS797399_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS797399_H (very low density lipoprotein cholesterol measurement, esterified cholesterol measurement QTL GWAS797399 (human)) Homo sapiens

Symbol: GWAS797399_H
Name: very low density lipoprotein cholesterol measurement, esterified cholesterol measurement QTL GWAS797399 (human)
RGD ID: 407148423
Trait: very low density lipoprotein cholesterol measurement, esterified cholesterol measurement
Measurement Type: blood very low density lipoprotein cholesterol level   (CMO:0000648)    
LOD Score: Not Available
P Value: 5.0E-32
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38162,690,372 - 62,690,373RGD_MAPPER_PIPELINEGRCh38
GRCh37163,156,043 - 63,156,044RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS797399_HHumanblood very low density lipoprotein cholesterol level  IAGPrs1168114405850206Based on the EFO term IDGWAS_CATALOGPMID:38448586

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS797399_HHumanesterified cholesterol measurement  IAGPrs1168114405850206 GWAS_CATALOGPMID:38448586
GWAS797399_HHumanvery low density lipoprotein cholesterol measurement  IAGPrs1168114405850206 GWAS_CATALOGPMID:38448586
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
127338266DOCK7-DTDOCK7 divergent transcript16268848262710694Human

Position Markers

Peak: (rs1168114)
Human AssemblyChrPosition (strand)Source
GRCh38162,690,372 - 62,690,373RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2314561GLUCO47_HGlucose level QTL 47 (human)1.1Glucose level14477336070773360Human
1578602LDLPS21_HLow density lipoprotein particle size QTL 21 (human)2.050.00037LDL particle size15253110578531105Human
407148423GWAS797399_Hvery low density lipoprotein cholesterol measurement, esterified cholesterol measurement QTL GWAS797399 (human)5e-32very low density lipoprotein cholesterol measurement, esterified cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)16269037262690373Human
1578620LDLPS20_HLow density lipoprotein particle size QTL 21 (human)2.040.00046LDL particle size15253110578531105Human
407137856GWAS786832_Hvery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio QTL GWAS786832 (human)2e-16very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)16269037262690373Human
407061092GWAS710068_Hhigh density lipoprotein cholesterol measurement QTL GWAS710068 (human)7e-15high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)16269037262690373Human
407410913GWAS1059889_Hphosphatidylinositol measurement QTL GWAS1059889 (human)3e-28phosphatidylinositol measurement16269037262690373Human
1578594LDLPS19_HLow density lipoprotein particle size QTL 19 (human)2.560.00009LDL particle size15253110578531105Human
407391142GWAS1040118_Heducational attainment QTL GWAS1040118 (human)6e-11educational attainment16269037262690373Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS710068_H GCST010242 HDL cholesterol levels 403,943 European ancestry individuals A 0.347628 7E-15 14.155 rs1168114 0.0155704 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:32203549
GWAS786832_H GCST90302058 Total cholesterol to total lipids ratio in medium VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.3383 2E-16 15.699 rs1168114 0.0342 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesterol:total lipids ratio (EFO:0020943)
 PMID:38448586
GWAS797399_H GCST90302152 Cholesterol esters in very small VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.338 5E-32 31.302 rs1168114 0.0488 very low density lipoprotein cholesterol measurement (EFO:0008317)
esterified cholesterol measurement (EFO:0008589)
 PMID:38448586
GWAS1040118_H GCST90105038 Educational attainment 3,037,499 European ancestry individuals A 0.3306 6E-11 10.222 rs1168114 0.00728596 educational attainment (EFO:0011015)
 PMID:35361970
GWAS1059889_H GCST90060912 Phosphatidylinositol(36:2)_[M-H]1- levels 5,662 Pakistani ancestry individuals G NR 3E-28 27.523 rs1168114 0.1448 phosphatidylinositol measurement (EFO:0010230)
 PMID:34503513
Database Acc Id Source(s)
GWAS Catalog GCST90302152 GWAS Catalog

RGD Curation Notes
Note Type Note Reference