GWAS795564_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS795564_H (chronic kidney disease QTL GWAS795564 (human)) Homo sapiens

Symbol: GWAS795564_H
Name: chronic kidney disease QTL GWAS795564 (human)
RGD ID: 407146588
Trait: chronic kidney disease
LOD Score: Not Available
P Value: 4.0E-6
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh382230,196,080 - 30,196,081RGD_MAPPER_PIPELINEGRCh38
GRCh372230,592,069 - 30,592,070RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1348799HORMAD2HORMA domain containing 2223007773230207456Human
16553258AC002378.1novel transcript223018281830207194Human

Position Markers

Peak: (rs2412980)
Human AssemblyChrPosition (strand)Source
GRCh382230,196,080 - 30,196,081RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581529BP71_HBlood pressure QTL 71 (human)20.001Blood pressurepulse pressure221109496637094966Human
2289428BW313_HBody weight QTL 313 (human)2.090.0015Body weightBMI221134428437344284Human
407146588GWAS795564_Hchronic kidney disease QTL GWAS795564 (human)0.000004chronic kidney disease223019608030196081Human
407291052GWAS940028_HHbA1c measurement QTL GWAS940028 (human)5e-14HbA1c measurementblood hemoglobin A1c level (CMO:0002786)223019608030196081Human
406975805GWAS624781_Hforced expiratory volume QTL GWAS624781 (human)7e-28forced expiratory volumeforced expiratory volume (CMO:0000254)223019608030196081Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS624781_H GCST90270081 FEV1 383,471 European ancestry individuals ? NR 7E-28 27.155 rs2412980 N/A forced expiratory volume (EFO:0004314)
 PMID:36641522
GWAS795564_H GCST001066 Dialysis-related mortality 610 African American type 2 diabetes cases ? 0.09 0.000004 5.398 rs2412980 1.65 chronic kidney disease (EFO:0003884)
 PMID:21546767
GWAS940028_H GCST90019509 Glycated hemoglobin levels 327,177 European ancestry individuals, 4,847 African ancestry individuals, 6,895 South Asian ancestry individuals C NR 5E-14 13.302 rs2412980 0.0319 HbA1c measurement (EFO:0004541)
 PMID:33462484
Database Acc Id Source(s)
GWAS Catalog GCST001066 GWAS Catalog

RGD Curation Notes
Note Type Note Reference