GWAS779394_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS779394_H (esterified cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS779394 (human)) Homo sapiens

Symbol: GWAS779394_H
Name: esterified cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS779394 (human)
RGD ID: 407130418
Trait: esterified cholesterol measurement, high density lipoprotein cholesterol measurement
Measurement Type: blood high density lipoprotein cholesterol level   (CMO:0000052)    
LOD Score: Not Available
P Value: 4.0E-21
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38773,620,599 - 73,620,600RGD_MAPPER_PIPELINEGRCh38
GRCh37773,034,929 - 73,034,930RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS779394_HHumanblood high density lipoprotein cholesterol level  IAGPrs71556736405850206Based on the EFO term IDGWAS_CATALOGPMID:38448586

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS779394_HHumanesterified cholesterol measurement  IAGPrs71556736405850206 GWAS_CATALOGPMID:38448586
GWAS779394_HHumanhigh density lipoprotein cholesterol measurement  IAGPrs71556736405850206 GWAS_CATALOGPMID:38448586
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1343873MLXIPLMLX interacting protein like77359320273647907Human

Position Markers

Peak: (rs71556736)
Human AssemblyChrPosition (strand)Source
GRCh38773,620,599 - 73,620,600RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407066291GWAS715267_Hhigh density lipoprotein particle size measurement QTL GWAS715267 (human)4e-49high density lipoprotein particle size measurementblood high density lipoprotein particle diameter (CMO:0002692)77362059973620600Human
407135638GWAS784614_Hhigh density lipoprotein cholesterol measurement QTL GWAS784614 (human)7e-39high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)77362059973620600Human
407130418GWAS779394_Hesterified cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS779394 (human)4e-21esterified cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)77362059973620600Human
407129970GWAS778946_Htotal cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS778946 (human)1e-24total cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)77362059973620600Human
407137251GWAS786227_Htotal lipids in very large HDL measurement QTL GWAS786227 (human)5e-38total lipids in very large HDL measurement 77362059973620600Human
407130275GWAS779251_Hfree cholesterol in very large HDL measurement QTL GWAS779251 (human)2e-33free cholesterol in very large HDL measurement 77362059973620600Human
406946477GWAS595453_Htriglyceride measurement QTL GWAS595453 (human)1e-10triglyceride measurementblood triglyceride level (CMO:0000118)77362059973620600Human
407113513GWAS762489_Hglutamine measurement QTL GWAS762489 (human)2e-25glutamine measurementblood amino acid measurement (CMO:0003730)77362059973620600Human
407140906GWAS789882_Hphospholipids in very large HDL measurement QTL GWAS789882 (human)2e-50phospholipids in very large HDL measurement 77362059973620600Human
407215947GWAS864923_Hlow density lipoprotein particle size measurement QTL GWAS864923 (human)6e-11low density lipoprotein particle size measurementblood low density lipoprotein particle diameter (CMO:0002693)77362059973620600Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS595453_H GCST011051 Postprandial triglyceride levels 5,630 individuals T 0.14 1E-10 10 rs71556736 0.17 triglyceride measurement (EFO:0004530)
 PMID:32603185
GWAS715267_H GCST90301972 Mean diameter of HDL particles 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.1291 4E-49 48.398 rs71556736 0.0869 high density lipoprotein particle size measurement (EFO:0008592)
 PMID:38448586
GWAS762489_H GCST90269558 Glutamine levels (UKB data field 23461) 88,070 European ancestry individuals T 0.131195 2E-25 24.699 rs71556736 0.0725036 glutamine measurement (EFO:0009768)
 PMID:36764567
GWAS778946_H GCST90302126 Total cholesterol levels in very large HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.1291 1E-24 24 rs71556736 0.0605 total cholesterol measurement (EFO:0004574)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS779251_H GCST90302130 Free cholesterol in very large HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.129 2E-33 32.699 rs71556736 0.0714 free cholesterol in very large HDL measurement (EFO:0022273)
 PMID:38448586
GWAS779394_H GCST90302128 Cholesterol esters in very large HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.1292 4E-21 20.398 rs71556736 0.0555 esterified cholesterol measurement (EFO:0008589)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS784614_H GCST90302133 Concentration of very large HDL particles 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.129 7E-39 38.155 rs71556736 0.0774 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS786227_H GCST90302132 Total lipids in very large HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.129 5E-38 37.302 rs71556736 0.0766 total lipids in very large HDL measurement (EFO:0022312)
 PMID:38448586
GWAS789882_H GCST90302134 Phospholipids in very large HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.129 2E-50 49.699 rs71556736 0.0886 phospholipids in very large HDL measurement (EFO:0022298)
 PMID:38448586
GWAS864923_H GCST90092889 Average diameter for LDL particles 115,082 European ancestry individuals C 0.868504 6E-11 10.222 rs71556736 0.0389267 low density lipoprotein particle size measurement (EFO:0008593)
 PMID:35213538
Database Acc Id Source(s)
GWAS Catalog GCST90302128 GWAS Catalog

RGD Curation Notes
Note Type Note Reference