GWAS775488_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS775488_H (esterified cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS775488 (human)) Homo sapiens

Symbol: GWAS775488_H
Name: esterified cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS775488 (human)
RGD ID: 407126512
Trait: esterified cholesterol measurement, high density lipoprotein cholesterol measurement
Measurement Type: blood high density lipoprotein cholesterol level   (CMO:0000052)    
LOD Score: Not Available
P Value: 8.0E-26
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381716,941,853 - 16,941,854RGD_MAPPER_PIPELINEGRCh38
GRCh371716,845,167 - 16,845,168RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS775488_HHumanblood high density lipoprotein cholesterol level  IAGPrs4792800405850206Based on the EFO term IDGWAS_CATALOGPMID:38448586

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS775488_HHumanesterified cholesterol measurement  IAGPrs4792800405850206 GWAS_CATALOGPMID:38448586
GWAS775488_HHumanhigh density lipoprotein cholesterol measurement  IAGPrs4792800405850206 GWAS_CATALOGPMID:38448586
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1344563TNFRSF13BTNF receptor superfamily member 13B171693908116972118Human

Position Markers

Peak: (rs4792800)
Human AssemblyChrPosition (strand)Source
GRCh381716,941,853 - 16,941,854RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407065219GWAS714195_Htotal cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS714195 (human)1e-09total cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)171694185316941854Human
407127846GWAS776822_Hphospholipids in small LDL measurement QTL GWAS776822 (human)8e-13phospholipids in small LDL measurement 171694185316941854Human
407187456GWAS836432_Hbilirubin measurement QTL GWAS836432 (human)5e-08bilirubin measurementserum total bilirubin level (CMO:0000376)171694185316941854Human
407226083GWAS875059_HAL amyloidosis QTL GWAS875059 (human)0.000002AL amyloidosis171694185316941854Human
407048333GWAS697309_Hserum IgG measurement QTL GWAS697309 (human)1e-12serum IgG measurementserum immunoglobulin G level (CMO:0002102)171694185316941854Human
407090605GWAS739581_Hcholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS739581 (human)3e-13cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)171694185316941854Human
407134411GWAS783387_Hfree cholesterol in very large HDL measurement QTL GWAS783387 (human)2e-24free cholesterol in very large HDL measurement 171694185316941854Human
407127670GWAS776646_Htotal cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS776646 (human)3e-26total cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)171694185316941854Human
407126512GWAS775488_Hesterified cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS775488 (human)8e-26esterified cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)171694185316941854Human
1298406BP16_HBlood pressure QTL 16 (human)0.0004Blood pressurehypertension susceptibility171477864740778647Human
407136755GWAS785731_Htotal lipids in very large HDL measurement QTL GWAS785731 (human)2e-17total lipids in very large HDL measurement 171694185316941854Human
407062814GWAS711790_Htotal cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS711790 (human)2e-10phospholipids in very large HDL measurement blood high density lipoprotein cholesterol level (CMO:0000052)171694185316941854Human
407135321GWAS784297_Hhigh density lipoprotein cholesterol measurement QTL GWAS784297 (human)6e-16high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)171694185316941854Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS697309_H GCST001600 IgG levels 1,999 Chinese ancestry male individuals G 0.50 1E-12 12 rs4792800 N/A serum IgG measurement (EFO:0004565)
 PMID:22673310
GWAS711790_H GCST90301969 Total cholesterol in HDL2 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8688 2E-10 9.699 rs4792800 0.0397 total cholesterol measurement (EFO:0004574)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS714195_H GCST90301971 Total cholesterol levels in HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8688 1E-9 9 rs4792800 0.0384 total cholesterol measurement (EFO:0004574)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS739581_H GCST90301996 Total cholesterol to total lipids ratio in large HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.87 3E-13 12.523 rs4792800 0.0456 cholesterol:total lipids ratio (EFO:0020943)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS775488_H GCST90302128 Cholesterol esters in very large HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8685 8E-26 25.097 rs4792800 0.0664 esterified cholesterol measurement (EFO:0008589)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS776646_H GCST90302126 Total cholesterol levels in very large HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8684 3E-26 25.523 rs4792800 0.0671 total cholesterol measurement (EFO:0004574)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS776822_H GCST90302099 Phospholipids in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8682 8E-13 12.097 rs4792800 0.0456 phospholipids in small LDL measurement (EFO:0022297)
 PMID:38448586
GWAS783387_H GCST90302130 Free cholesterol in very large HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8687 2E-24 23.699 rs4792800 0.0643 free cholesterol in very large HDL measurement (EFO:0022273)
 PMID:38448586
GWAS784297_H GCST90302133 Concentration of very large HDL particles 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.868 6E-16 15.222 rs4792800 0.0515 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS785731_H GCST90302132 Total lipids in very large HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.868 2E-17 16.699 rs4792800 0.0542 total lipids in very large HDL measurement (EFO:0022312)
 PMID:38448586
None Available GCST90302134 Phospholipids in very large HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8685 2E-10 9.699 rs4792800 0.04 phospholipids in very large HDL measurement (EFO:0022298)
 PMID:38448586
GWAS836432_H GCST90018753 Total bilirubin levels 124,341 East Asian ancestry individuals G 0.373218 5E-8 7.302 rs4792800 0.0213705 bilirubin measurement (EFO:0004570)
 PMID:34594039
GWAS875059_H GCST004028 Immunoglobulin light chain (AL) amyloidosis 1,229 cases, 7,526 controls G 0.12 0.000002 5.699 rs4792800 1.36 PMID:28025584
Database Acc Id Source(s)
GWAS Catalog GCST90302128 GWAS Catalog

RGD Curation Notes
Note Type Note Reference