GWAS774902_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS774902_H (esterified cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS774902 (human)) Homo sapiens

Symbol: GWAS774902_H
Name: esterified cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS774902 (human)
RGD ID: 407125926
Trait: esterified cholesterol measurement, low density lipoprotein cholesterol measurement
Measurement Type: blood low density lipoprotein cholesterol level   (CMO:0000053)    
LOD Score: Not Available
P Value: 9.0E-17
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38616,114,017 - 16,114,018RGD_MAPPER_PIPELINEGRCh38
GRCh37616,114,248 - 16,114,249RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS774902_HHumanblood low density lipoprotein cholesterol level  IAGPrs1569446405850206Based on the EFO term IDGWAS_CATALOGPMID:38448586

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS774902_HHumanesterified cholesterol measurement  IAGPrs1569446405850206 GWAS_CATALOGPMID:38448586
GWAS774902_HHumanlow density lipoprotein cholesterol measurement  IAGPrs1569446405850206 GWAS_CATALOGPMID:38448586
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs1569446)
Human AssemblyChrPosition (strand)Source
GRCh38616,114,017 - 16,114,018RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2289408BW324_HBody weight QTL 324 (human)3.150.0001Body fat amount6120803913Human
407122502GWAS771478_Hcholesterol:total lipids ratio, cholesteryl esters:total lipids ratio QTL GWAS771478 (human)3e-15cholesterol:total lipids ratio, cholesteryl esters:total lipids ratio61611401716114018Human
407125926GWAS774902_Hesterified cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS774902 (human)9e-17esterified cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)61611401716114018Human
1643418BW282_HBody Weight QTL 282 (human)2.070.001Body weight6119321359Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
2289320BW390_HBody weight QTL 390 (human)2.13Body weightBMI6119321359Human
407096617GWAS745593_Hcholesterol esters in medium LDL measurement QTL GWAS745593 (human)7e-17cholesterol esters in medium LDL measurement61611401716114018Human
407129931GWAS778907_Htotal cholesterol in small LDL QTL GWAS778907 (human)2e-16total cholesterol in small LDL61611401716114018Human
1358854MULTSCL4_HMultiple sclerosis susceptibility QTL 4 (human)Multiple sclerosis susceptibility6691196032911960Human
2289435BMD4_HBone mineral density QTL 4 (human)3.150.0001Bone mineral density6120803913Human
2292824PRSTS5_HProstate tumor susceptibility QTL 5 (human)Prostate tumor susceptibility6119232373Human
1643495BW291_HBody Weight QTL 291 (human)2.13Body weightBMI6119321359Human
1643399BMD5_HBone mineral density QTL 5 (human)2.320.0005Bone mineral density6691196032911960Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS745593_H GCST90302045 Cholesterol esters in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.5273 7E-17 16.155 rs1569446 0.0343 cholesterol esters in medium LDL measurement (EFO:0022186)
 PMID:38448586
GWAS771478_H GCST90302094 Cholesteryl esters to total lipids ratio in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.5275 3E-15 14.523 rs1569446 0.0322 cholesterol:total lipids ratio (EFO:0020943)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:38448586
GWAS774902_H GCST90302093 Cholesterol esters in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.5272 9E-17 16.046 rs1569446 0.0342 esterified cholesterol measurement (EFO:0008589)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS778907_H GCST90302091 Total Cholesterol in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.5273 2E-16 15.699 rs1569446 0.0337 total cholesterol in small LDL (EFO:0022179)
 PMID:38448586
Database Acc Id Source(s)
GWAS Catalog GCST90302093 GWAS Catalog

RGD Curation Notes
Note Type Note Reference