GWAS756405_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS756405_H (leukocyte count QTL GWAS756405 (human)) Homo sapiens

Symbol: GWAS756405_H
Name: leukocyte count QTL GWAS756405 (human)
RGD ID: 407107429
Trait: leukocyte quantity   (VT:0000217)    
Measurement Type: white blood cell count   (CMO:0000027)    
LOD Score: Not Available
P Value: 2.0E-20
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38123,524,098 - 23,524,099RGD_MAPPER_PIPELINEGRCh38
GRCh37123,850,590 - 23,850,591RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS756405_HHumanwhite blood cell count  IAGPrs60918921405850206Based on the EFO term IDGWAS_CATALOGPMID:32888494

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS756405_HHumanleukocyte quantity  IAGPrs60918921405850206Based on the EFO term IDGWAS_CATALOGPMID:32888494

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS756405_HHumanleukocyte count  IAGPrs60918921405850206 GWAS_CATALOGPMID:32888494
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Vertebrate Trait

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1348982E2F2E2F transcription factor 212350521223531233Human
38657108LOC101928163uncharacterized LOC10192816312352193023528419Human

Position Markers

Peak: (rs60918921)
Human AssemblyChrPosition (strand)Source
GRCh38123,524,098 - 23,524,099RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
407133717GWAS782693_Hneutrophil count QTL GWAS782693 (human)3e-16neutrophil quantity (VT:0000222)blood neutrophil count (CMO:0000030)12352409823524099Human
407107429GWAS756405_Hleukocyte count QTL GWAS756405 (human)2e-20leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)12352409823524099Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS756405_H GCST90002407 White blood cell count 408,112 British individuals A 0.617903 2E-20 19.699 rs60918921 0.021498175 leukocyte count (EFO:0004308)
 PMID:32888494
GWAS782693_H GCST90002398 Neutrophil count 408,112 British individuals A 0.617938 3E-16 15.523 rs60918921 0.018965894 neutrophil count (EFO:0004833)
 PMID:32888494
Database Acc Id Source(s)
GWAS Catalog GCST90002407 GWAS Catalog

RGD Curation Notes
Note Type Note Reference