GWAS754237_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS754237_H (erythrocyte count QTL GWAS754237 (human)) Homo sapiens

Symbol: GWAS754237_H
Name: erythrocyte count QTL GWAS754237 (human)
RGD ID: 407105261
Trait: erythrocyte count
Measurement Type: red blood cell count   (CMO:0000025)    
LOD Score: Not Available
P Value: 3.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38111,797,979 - 11,797,980RGD_MAPPER_PIPELINEGRCh38
GRCh37111,858,036 - 11,858,037RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS754237_HHumanred blood cell count  IAGPrs17037388405850206Based on the EFO term IDGWAS_CATALOGPMID:32888494

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS754237_HHumanerythrocyte count  IAGPrs17037388405850206 GWAS_CATALOGPMID:32888494
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
733483MTHFRmethylenetetrahydrofolate reductase11178572311805964Human

Position Markers

Peak: (rs17037388)
Human AssemblyChrPosition (strand)Source
GRCh38111,797,979 - 11,797,980RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
407063501GWAS712477_Hmean platelet volume QTL GWAS712477 (human)7e-13erythrocyte countred blood cell count (CMO:0000025)11179797911797980Human
407105261GWAS754237_Herythrocyte count QTL GWAS754237 (human)3e-09erythrocyte countred blood cell count (CMO:0000025)11179797911797980Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS712477_H GCST90002395 Mean platelet volume 408,112 British individuals G 0.163065 7E-13 12.155 rs17037388 0.02163056 mean platelet volume (EFO:0004584)
 PMID:32888494
None Available GCST007069 Red blood cell count approximately 445,000 European ancestry individuals ? NR 7E-13 12.155 rs17037388 N/A erythrocyte count (EFO:0004305)
 PMID:30595370
GWAS754237_H GCST90002403 Red blood cell count 408,112 British individuals G 0.163337 3E-9 8.523 rs17037388 0.017598467 erythrocyte count (EFO:0004305)
 PMID:32888494
Database Acc Id Source(s)
GWAS Catalog GCST90002403 GWAS Catalog

RGD Curation Notes
Note Type Note Reference