GWAS744594_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS744594_H (free cholesterol in large LDL measurement QTL GWAS744594 (human)) Homo sapiens

Symbol: GWAS744594_H
Name: free cholesterol in large LDL measurement QTL GWAS744594 (human)
RGD ID: 407095618
Trait: cholesterol esters in medium LDL measurement
LOD Score: Not Available
P Value: 7.0E-12
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38632,373,621 - 32,373,622RGD_MAPPER_PIPELINEGRCh38
GRCh37632,341,398 - 32,341,399RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS744594_HHumancholesterol esters in medium LDL measurement  IAGPrs9391858405850206 GWAS_CATALOGPMID:38448586
GWAS744594_HHumanfree cholesterol in large LDL measurement  IAGPrs9391858405850206 GWAS_CATALOGPMID:38448586
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
13782242TSBP1-AS1TSBP1 and BTNL2 antisense RNA 163225517332407730Human

Position Markers

Peak: (rs9391858)
Human AssemblyChrPosition (strand)Source
GRCh38632,373,621 - 32,373,622RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407081923GWAS730899_Hfree cholesterol in IDL measurement QTL GWAS730899 (human)6e-12free cholesterol in IDL measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)63237362132373622Human
407095618GWAS744594_Hfree cholesterol in large LDL measurement QTL GWAS744594 (human)7e-12free cholesterol in large LDL measurement63237362132373622Human
407080651GWAS729627_Hlow density lipoprotein cholesterol measurement, lipid measurement QTL GWAS729627 (human)1e-13total lipids in large LDLblood lipid measurement (CMO:0000050)63237362132373622Human
407129932GWAS778908_Htotal cholesterol in small LDL QTL GWAS778908 (human)7e-13total cholesterol in small LDL63237362132373622Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
407082762GWAS731738_Hcholesterol esters in large LDL measurement QTL GWAS731738 (human)4e-13cholesterol esters in large LDL measurement63237362132373622Human
407093388GWAS742364_Hfree cholesterol in medium LDL measurement QTL GWAS742364 (human)3e-13phospholipids in large LDL measurementblood low density lipoprotein phospholipid level (CMO:0001568)63237362132373622Human
407125963GWAS774939_Hlow density lipoprotein cholesterol measurement QTL GWAS774939 (human)1e-14low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)63237362132373622Human
407082444GWAS731420_Hlow density lipoprotein cholesterol measurement QTL GWAS731420 (human)7e-14low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)63237362132373622Human
1358854MULTSCL4_HMultiple sclerosis susceptibility QTL 4 (human)Multiple sclerosis susceptibility6691196032911960Human
407122898GWAS771874_Htotal cholesterol in medium LDL QTL GWAS771874 (human)4e-12total cholesterol in medium LDL63237362132373622Human
407069140GWAS718116_Htotal cholesterol in IDL QTL GWAS718116 (human)1e-12esterified cholesterol measurement, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)63237362132373622Human
407076052GWAS725028_Hfree cholesterol measurement QTL GWAS725028 (human)6e-13total cholesterol in large LDLblood cholesterol level (CMO:0002280)63237362132373622Human
407144412GWAS793388_Hsphingomyelin measurement QTL GWAS793388 (human)1e-09sphingomyelin measurement63237362132373622Human
1358857MULTSCL19_HMultiple sclerosis susceptibility QTL 19 (human)Multiple sclerosis susceptibility61958431145584311Human
1643399BMD5_HBone mineral density QTL 5 (human)2.320.0005Bone mineral density6691196032911960Human
407118820GWAS767796_Htotal lipids in IDL QTL GWAS767796 (human)2e-14total lipids in IDLblood total cholesterol level (CMO:0000051)63237362132373622Human
407126692GWAS775668_Hfree cholesterol in small LDL measurement QTL GWAS775668 (human)6e-15free cholesterol in small LDL measurement 63237362132373622Human
1358839MULTSCL5_HMultiple sclerosis susceptibility QTL 5 (human)Multiple sclerosis susceptibility61958431145584311Human
407125927GWAS774903_Hesterified cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS774903 (human)3e-12esterified cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)63237362132373622Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
407091947GWAS740923_Htotal cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS740923 (human)9e-13low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)63237362132373622Human
1298431RA11_HRheumatoid arthritis QTL 11 (human)0.0000024Joint/bone inflammationrheumatoid arthritis61991188340191709Human
407058416GWAS707392_Hesterified cholesterol measurement QTL GWAS707392 (human)3e-14esterified cholesterol measurement63237362132373622Human
407107056GWAS756032_Hlow density lipoprotein cholesterol measurement QTL GWAS756032 (human)4e-14low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)63237362132373622Human
407065528GWAS714504_Htotal cholesterol measurement QTL GWAS714504 (human)3e-08total cholesterol measurementblood total cholesterol level (CMO:0000051)63237362132373622Human
407082686GWAS731662_Hphospholipids in medium LDL measurement QTL GWAS731662 (human)8e-15phospholipids in medium LDL measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)63237362132373622Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS707392_H GCST90301957 Esterified cholesterol levels 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8229 3E-14 13.523 rs9391858 0.0407 esterified cholesterol measurement (EFO:0008589)
 PMID:38448586
GWAS714504_H GCST90010363 Total cholesterol levels 29,902 European ancestry individuals G 0.14 3E-8 7.523 rs9391858 2.4 total cholesterol measurement (EFO:0004574)
 PMID:31566214
GWAS718116_H GCST90301975 Total Cholesterol in IDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.823 1E-12 12 rs9391858 0.0381 total cholesterol in IDL (EFO:0022184)
 PMID:38448586
GWAS725028_H GCST90301963 Free cholesterol levels 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8231 6E-13 12.222 rs9391858 0.0384 free cholesterol measurement (EFO:0008591)
 PMID:38448586
GWAS729627_H GCST90302049 Total lipid levels in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8227 1E-13 13 rs9391858 0.0397 low density lipoprotein cholesterol measurement (EFO:0004611)
lipid measurement (EFO:0004529)
 PMID:38448586
None Available GCST90301977 Cholesterol esters in IDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.823 1E-12 12 rs9391858 0.0381 esterified cholesterol measurement (EFO:0008589)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:38448586
GWAS730899_H GCST90301979 Free cholesterol in IDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.823 6E-12 11.222 rs9391858 0.0367 free cholesterol in IDL measurement (EFO:0022181)
 PMID:38448586
GWAS731420_H GCST90302050 Concentration of medium LDL particles 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8227 7E-14 13.155 rs9391858 0.0402 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS731662_H GCST90302051 Phospholipids in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8227 8E-15 14.097 rs9391858 0.0417 phospholipids in medium LDL measurement (EFO:0022183)
 PMID:38448586
GWAS731738_H GCST90302009 Cholesterol esters in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8227 4E-13 12.398 rs9391858 0.0389 cholesterol esters in large LDL measurement (EFO:0022165)
 PMID:38448586
None Available GCST90302007 Total cholesterol in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8227 6E-13 12.222 rs9391858 0.0386 total cholesterol in large LDL (EFO:0022167)
 PMID:38448586
None Available GCST90301982 Concentration of IDL particles 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8229 8E-15 14.097 rs9391858 0.0416 intermediate density lipoprotein measurement (EFO:0008595)
 PMID:38448586
GWAS740923_H GCST90301991 Total cholesterol levels in LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8228 9E-13 12.046 rs9391858 0.0384 total cholesterol measurement (EFO:0004574)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS742364_H GCST90302047 Free cholesterol in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8229 3E-13 12.523 rs9391858 0.0392 free cholesterol in medium LDL measurement (EFO:0022268)
 PMID:38448586
GWAS744594_H GCST90302011 Free cholesterol in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8229 7E-12 11.155 rs9391858 0.0367 free cholesterol in large LDL measurement (EFO:0022176)
 PMID:38448586
None Available GCST90302045 Cholesterol esters in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8227 7E-12 11.155 rs9391858 0.0369 cholesterol esters in medium LDL measurement (EFO:0022186)
 PMID:38448586
GWAS756032_H GCST90302014 Concentration of large LDL particles 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8228 4E-14 13.398 rs9391858 0.0405 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
None Available GCST90302013 Total lipids in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8228 1E-13 13 rs9391858 0.0399 total lipids in large LDL (EFO:0022163)
 PMID:38448586
None Available GCST90302016 Phospholipids to total lipids ratio in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8215 9E-13 12.046 rs9391858 0.0393 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:38448586
GWAS767796_H GCST90301981 Total lipids in IDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8229 2E-14 13.699 rs9391858 0.0411 total lipids in IDL (EFO:0022161)
 PMID:38448586
None Available GCST90302015 Phospholipids in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8227 3E-13 12.523 rs9391858 0.0393 phospholipids in large LDL measurement (EFO:0022174)
 PMID:38448586
GWAS771874_H GCST90302043 Total cholesterol in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8227 4E-12 11.398 rs9391858 0.0373 total cholesterol in medium LDL (EFO:0022185)
 PMID:38448586
None Available GCST90302075 Serum total cholesterol levels 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.823 2E-14 13.699 rs9391858 0.041 total cholesterol measurement (EFO:0004574)
 PMID:38448586
GWAS774903_H GCST90302093 Cholesterol esters in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8227 3E-12 11.523 rs9391858 0.0375 esterified cholesterol measurement (EFO:0008589)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS774939_H GCST90302098 Concentration of small LDL particles 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8227 1E-14 14 rs9391858 0.0413 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS775668_H GCST90302095 Free cholesterol in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.823 6E-15 14.222 rs9391858 0.0418 free cholesterol in small LDL measurement (EFO:0022271)
 PMID:38448586
None Available GCST90302099 Phospholipids in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8227 1E-14 14 rs9391858 0.0415 phospholipids in small LDL measurement (EFO:0022297)
 PMID:38448586
None Available GCST90302097 Total lipids in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8227 2E-14 13.699 rs9391858 0.041 total lipids in small LDL (EFO:0022168)
 PMID:38448586
GWAS778908_H GCST90302091 Total Cholesterol in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8227 7E-13 12.155 rs9391858 0.0385 total cholesterol in small LDL (EFO:0022179)
 PMID:38448586
GWAS793388_H GCST90302103 Sphingomyelins levels 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals A 0.8219 1E-9 9 rs9391858 0.0333 sphingomyelin measurement (EFO:0010118)
 PMID:38448586
Database Acc Id Source(s)
GWAS Catalog GCST90302011 GWAS Catalog
  GCST90302045 GWAS Catalog

RGD Curation Notes
Note Type Note Reference