GWAS719676_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS719676_H (balding measurement QTL GWAS719676 (human)) Homo sapiens

Symbol: GWAS719676_H
Name: balding measurement QTL GWAS719676 (human)
RGD ID: 407070700
Trait: balding measurement
Measurement Type: coat/hair morphological measurement   (CMO:0001807)    
LOD Score: Not Available
P Value: 6E-93
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38124,965,206 - 24,965,207RGD_MAPPER_PIPELINEGRCh38
GRCh37125,291,697 - 25,291,698RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS719676_HHumancoat/hair morphological measurement  IAGPrs188468174405850206Based on the EFO term IDGWAS_CATALOGPMID:30573740

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS719676_HHumanbalding measurement  IAGPrs188468174405850206 GWAS_CATALOGPMID:30573740
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs188468174)
Human AssemblyChrPosition (strand)Source
GRCh38124,965,206 - 24,965,207RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
406952258GWAS601234_Hinterleukin-5 receptor subunit alpha measurement QTL GWAS601234 (human)1e-18interleukin-5 receptor subunit alpha measurement12496520624965207Human
406940616GWAS589592_HSLAM family member 7 measurement QTL GWAS589592 (human)4e-25SLAM family member 7 measurement12496520624965207Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
406952975GWAS601951_Hprotein measurement QTL GWAS601951 (human)5e-17protein measurement12496520624965207Human
407348872GWAS997848_Hbalding measurement QTL GWAS997848 (human)2e-42balding measurementcoat/hair morphological measurement (CMO:0001807)12496520624965207Human
407218901GWAS867877_Hreticulocyte count QTL GWAS867877 (human)3e-13reticulocyte counttotal reticulocyte count (CMO:0003020)12496520624965207Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
407391325GWAS1040301_Hserum IgG glycosylation measurement QTL GWAS1040301 (human)9e-16serum IgG glycosylation measurement12496520624965207Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
406939292GWAS588268_Hprotein measurement QTL GWAS588268 (human)8e-120protein measurement12496520624965207Human
407135524GWAS784500_Hfree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS784500 (human)9e-13free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)12496520624965207Human
406970785GWAS619761_Hglutaminyl-peptide cyclotransferase measurement QTL GWAS619761 (human)5e-14glutaminyl-peptide cyclotransferase measurement12496520624965207Human
407089511GWAS738487_Halopecia QTL GWAS738487 (human)5e-21alopecia12496520624965207Human
407372386GWAS1021362_Hbasophil count QTL GWAS1021362 (human)4e-10basophil quantity (VT:0002607)blood basophil count (CMO:0000034)12496520624965207Human
406949610GWAS598586_HCD5 antigen-like measurement QTL GWAS598586 (human)6e-38CD5 antigen-like measurement12496520624965207Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
407070700GWAS719676_Hbalding measurement QTL GWAS719676 (human)6e-93balding measurementcoat/hair morphological measurement (CMO:0001807)12496520624965207Human
407393464GWAS1042440_Hserum IgG glycosylation measurement QTL GWAS1042440 (human)6e-17serum IgG glycosylation measurement12496520624965207Human
407218741GWAS867717_Hserum IgA measurement QTL GWAS867717 (human)8e-55serum IgA measurementserum immunoglobulin A level (CMO:0002095)12496520624965207Human
407393459GWAS1042435_Hserum IgG glycosylation measurement QTL GWAS1042435 (human)3e-12serum IgG glycosylation measurement12496520624965207Human
407220158GWAS869134_Hreticulocyte measurement QTL GWAS869134 (human)4e-12reticulocyte morphology trait (VT:0002424)serum immunoglobulin A level (CMO:0002095)12496520624965207Human
407393460GWAS1042436_Hserum IgG glycosylation measurement QTL GWAS1042436 (human)1e-11serum IgG glycosylation measurement12496520624965207Human
406972541GWAS621517_Himmunoglobulin M measurement QTL GWAS621517 (human)7e-12blood immunoglobulin M amount (VT:0010481)blood immunoglobulin M level (CMO:0002092)12496520624965207Human
406947708GWAS596684_Hmicrofibrillar-associated protein 2 measurement QTL GWAS596684 (human)2e-15microfibrillar-associated protein 2 measurement12496520624965207Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS588268_H GCST90248001 Immunoglobulin A levels 10,708 European ancestry individuals T 0.01 8E-120 119.097 rs188468174 1.369 protein measurement (EFO:0004747)
 PMID:34648354
GWAS589592_H GCST90249565 SLAM family member 7 levels 10,708 European ancestry individuals T 0.01 4E-25 24.398 rs188468174 0.62 SLAM family member 7 measurement (EFO:0008287)
 PMID:34648354
GWAS596684_H GCST90248458 Microfibrillar-associated protein 2 levels 10,708 European ancestry individuals T 0.01 2E-15 14.699 rs188468174 0.472 microfibrillar-associated protein 2 measurement (EFO:0801801)
 PMID:34648354
GWAS598586_H GCST90246946 CD5 antigen-like levels 10,708 European ancestry individuals T 0.01 6E-38 37.222 rs188468174 0.774 CD5 antigen-like measurement (EFO:0020248)
 PMID:34648354
GWAS601234_H GCST90248075 Interleukin-5 receptor subunit alpha levels 10,708 European ancestry individuals T 0.01 1E-18 18 rs188468174 0.517 interleukin-5 receptor subunit alpha measurement (EFO:0801730)
 PMID:34648354
GWAS601951_H GCST90249709 Serine/threonine-protein phosphatase 4 regulatory subunit 3A levels 10,708 European ancestry individuals T 0.01 5E-17 16.302 rs188468174 0.474 protein measurement (EFO:0004747)
 PMID:34648354
GWAS619761_H GCST90247789 Glutaminyl-peptide cyclotransferase levels 10,708 European ancestry individuals T 0.01 5E-14 13.302 rs188468174 0.428 glutaminyl-peptide cyclotransferase measurement (EFO:0802570)
 PMID:34648354
GWAS621517_H GCST90248020 Immunoglobulin M levels 10,708 European ancestry individuals T 0.01 7E-12 11.155 rs188468174 0.398 immunoglobulin M measurement (EFO:0020466)
 PMID:34648354
GWAS719676_H GCST007020 Male-pattern baldness 205,327 European ancestry males T 0.0140221 6E-93 92.222 rs188468174 0.266837 balding measurement (EFO:0007825)
 PMID:30573740
GWAS738487_H GCST006661 Male-pattern baldness 52,874 British ancestry males T NR 5E-21 20.302 rs188468174 0.238642 PMID:28196072
GWAS784500_H GCST90302131 Free cholesterol to total lipids ratio in very large HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.0133 9E-13 12.046 rs188468174 0.1555 free cholesterol:total lipids ratio (EFO:0020945)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS867717_H GCST008568 IgA levels 16,883 Icelandic ancestry individuals T 0.0084 8E-55 54.097 rs188468174 0.9 serum IgA measurement (EFO:0004912)
 PMID:28628107
GWAS867877_H GCST90002405 Reticulocyte count 408,112 British individuals T 0.0143180000000001 3E-13 12.523 rs188468174 0.06925445 reticulocyte count (EFO:0007986)
 PMID:32888494
GWAS869134_H GCST90002406 Reticulocyte fraction of red cells 408,112 British individuals T 0.0143140000000001 4E-12 11.398 rs188468174 0.06596895 reticulocyte measurement (EFO:0010700)
 PMID:32888494
GWAS997848_H GCST007038 Balding type 1 approximately 208,000 European ancestry individuals ? NR 2E-42 41.699 rs188468174 N/A balding measurement (EFO:0007825)
 PMID:30595370
GWAS1021362_H GCST90002292 Basophil count 474,001 European ancestry individuals C 0.985766 4E-10 9.398 rs188468174 0.055334 basophil count (EFO:0005090)
 PMID:32888493
GWAS1040301_H GCST90129343 Immunoglobulin N-glycan 23 levels 2,020 Korculan or Shetland Isles (founder/genetic isolate) individuals T 0.014 9E-16 15.046 rs188468174 1.251 serum IgG glycosylation measurement (EFO:0005193)
 PMID:35332118
GWAS1042435_H GCST90129328 Immunoglobulin N-glycan 8 levels 2,020 Korculan or Shetland Isles (founder/genetic isolate) individuals T 0.014 3E-12 11.523 rs188468174 1.12 serum IgG glycosylation measurement (EFO:0005193)
 PMID:35332118
GWAS1042436_H GCST90129330 Immunoglobulin N-glycan 10 levels 2,020 Korculan or Shetland Isles (founder/genetic isolate) individuals T 0.014 1E-11 11 rs188468174 1.124 serum IgG glycosylation measurement (EFO:0005193)
 PMID:35332118
GWAS1042440_H GCST90129331 Immunoglobulin N-glycan 11 levels 2,020 Korculan or Shetland Isles (founder/genetic isolate) individuals T 0.014 6E-17 16.222 rs188468174 1.266 serum IgG glycosylation measurement (EFO:0005193)
 PMID:35332118
None Available GCST90137505 IgA levels 1,852 African American or Afro-Caribbean individuals ? NR 4E-12 11.398 rs188468174 1.49 serum IgA measurement (EFO:0004912)
 PMID:34814699
None Available GCST90092821 Glycoprotein acetyls levels 115,082 European ancestry individuals C 0.985159 4E-10 9.398 rs188468174 0.107527 glycoprotein measurement (EFO:0004555)
 PMID:35213538
Database Acc Id Source(s)
GWAS Catalog GCST007020 GWAS Catalog

RGD Curation Notes
Note Type Note Reference