GWAS711107_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS711107_H (celiac disease QTL GWAS711107 (human)) Homo sapiens

Symbol: GWAS711107_H
Name: celiac disease QTL GWAS711107 (human)
RGD ID: 407062131
Trait: celiac disease
LOD Score: Not Available
P Value: 1.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3812,603,539 - 2,603,540RGD_MAPPER_PIPELINEGRCh38
GRCh3712,534,978 - 2,534,979RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1603610MMEL1membrane metalloendopeptidase like 1125906392633016Human

Position Markers

Peak: (rs6664969)
Human AssemblyChrPosition (strand)Source
GRCh3812,603,539 - 2,603,540RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
407062627GWAS711603_Hautoimmune disease QTL GWAS711603 (human)3e-10autoimmune disease126035392603540Human
407062131GWAS711107_Hceliac disease QTL GWAS711107 (human)1e-08rheumatoid arthritis126035392603540Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS711107_H GCST009874 Celiac disease 11,489 European ancestry cases, 22,308 European ancestry controls ? NR 1E-8 8 rs6664969 1.1169313 celiac disease (EFO:0001060)
 PMID:30572963
None Available GCST009877 Rheumatoid arthritis 15,523 European ancestry cases, 22,308 European ancestry controls ? 0.67 1E-8 8 rs6664969 1.1078187 rheumatoid arthritis (EFO:0000685)
 PMID:30572963
GWAS711603_H GCST009873 Autoimmune traits (pleiotropy) 11,489 European ancestry cases with celiac disease, 15,523 European ancestry cases with rheumatoid arthritis, 3,477 European ancestry cases with systemic sclerosis, 6,670 European ancestry cases with type 1 diabetes, 22,308 European ancestry controls A NA 3E-10 9.523 rs6664969 N/A autoimmune disease (EFO:0005140)
 PMID:30572963
Database Acc Id Source(s)
GWAS Catalog GCST009874 GWAS Catalog
  GCST009877 GWAS Catalog

RGD Curation Notes
Note Type Note Reference