GWAS677638_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS677638_H (age at menarche QTL GWAS677638 (human)) Homo sapiens

Symbol: GWAS677638_H
Name: age at menarche QTL GWAS677638 (human)
RGD ID: 407028662
Trait: age at menarche
LOD Score: Not Available
P Value: 3.0E-6
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3811117,518,217 - 117,518,218RGD_MAPPER_PIPELINEGRCh38
GRCh3711117,388,932 - 117,388,933RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS677638_HHumanage at menarche  IAGPrs11216435405850206 GWAS_CATALOGPMID:23599027
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1312583DSCAML1DS cell adhesion molecule like 111117427772117817514Human

Position Markers

Peak: (rs11216435)
Human AssemblyChrPosition (strand)Source
GRCh3811117,518,217 - 117,518,218RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407048754GWAS697730_Hfructose measurement, glucose measurement, galactose measurement QTL GWAS697730 (human)0.0000003fructose absorption trait (VT:0001668)blood glucose level (CMO:0000046)11117518217117518218Human
407028662GWAS677638_Hage at menarche QTL GWAS677638 (human)0.000003age at menarche11117518217117518218Human
1559115SCL20_HSerum cholesterol level QTL 20 (human)3.220.001213Lipid levelLDL cholesterol11100442501126442501Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS1704475_H GCST010699 Brain morphology (min-P) 26,502 European ancestry individuals ? NR 5E-9 8.302 rs11216435 N/A brain attribute (OBA:2045210)
neuroimaging measurement (EFO:0004346)
 PMID:32665545
GWAS1705459_H GCST010698 Subcortical volume (min-P) 26,502 European ancestry individuals ? NR 1E-9 9 rs11216435 N/A brain volume (OBA:2050009)
neuroimaging measurement (EFO:0004346)
 PMID:32665545
GWAS677638_H GCST001973 Menarche (age at onset) 18,089 African American individuals T 0.32 0.000003 5.523 rs11216435 4.41 age at menarche (EFO:0004703)
 PMID:23599027
GWAS697730_H GCST009391 Metabolite levels 2,076 European ancestry individuals ? NR 3E-7 6.523 rs11216435 0.2358491 fructose measurement (EFO:0010477)
glucose measurement (EFO:0004468)
galactose measurement (EFO:0010481)
 PMID:23823483
Database Acc Id Source(s)
GWAS Catalog GCST001973 GWAS Catalog

RGD Curation Notes
Note Type Note Reference