GWAS675157_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS675157_H (preeclampsia, hypertension, pregnancy-induced QTL GWAS675157 (human)) Homo sapiens

Symbol: GWAS675157_H
Name: preeclampsia, hypertension, pregnancy-induced QTL GWAS675157 (human)
RGD ID: 407026181
Trait: preeclampsia, hypertension, pregnancy-induced
LOD Score: Not Available
P Value: 7.0E-12
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38111,805,747 - 11,805,748RGD_MAPPER_PIPELINEGRCh38
GRCh37111,865,804 - 11,865,805RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
pre-eclampsia  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Preeclampsia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
733483MTHFRmethylenetetrahydrofolate reductase11178572311805964Human
329406428LOC129929416ATAC-STARR-seq lymphoblastoid silent region 27311180571911805768Human

Position Markers

Peak: (rs13306561)
Human AssemblyChrPosition (strand)Source
GRCh38111,805,747 - 11,805,748RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
406917057GWAS566033_Hhypertension, pregnancy-induced QTL GWAS566033 (human)0.0000001hypertension, pregnancy-induced11180574711805748Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
406991171GWAS640147_Hred blood cell folate measurement QTL GWAS640147 (human)9e-12red blood cell folate measurement11180574711805748Human
407026181GWAS675157_Hpreeclampsia, hypertension, pregnancy-induced QTL GWAS675157 (human)7e-12preeclampsia, hypertension, pregnancy-induced11180574711805748Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
407075695GWAS724671_Hpulse pressure measurement, alcohol drinking QTL GWAS724671 (human)6e-16pulse pressure measurement, alcohol drinkingpulse pressure (CMO:0000292)11180574711805748Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS566033_H GCST90245819 Hypertension complicating pregnancy 10,097 European ancestry cases, 331,138 European ancestry controls ? NR 1E-7 7 rs13306561 N/A PMID:36553520
GWAS640147_H GCST007580 Red blood cell folate levels 2,232 Irish ancestry individuals ? NR 9E-12 11.046 rs13306561 0.04649 red blood cell folate measurement (EFO:0009703)
 PMID:30339177
GWAS675157_H GCST90269904 Preeclampsia or other maternal hypertension (maternal genotype effect) 15,200 European ancestry cases, 115,007 European ancestry controls G 0.14 7E-12 11.155 rs13306561 0.88 preeclampsia (EFO:0000668)
 PMID:37285119
GWAS724671_H GCST006168 Pulse pressure x alcohol consumption interaction (2df test) 91,099 European ancestry drinkers and non-drinkers, 21,416 African American or Afro-Caribbean drinkers and non-drinkers, 12,365 Asian ancestry drinkers and non-drinkers, 8,470 Hispanic or Latin American drinkers and non-drinkers A 0.86 6E-16 15.222 rs13306561 N/A pulse pressure measurement (EFO:0005763)
alcohol drinking (EFO:0004329)
 PMID:29912962
Database Acc Id Source(s)
GWAS Catalog GCST90269904 GWAS Catalog

RGD Curation Notes
Note Type Note Reference