GWAS640001_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS640001_H (alcohol consumption measurement QTL GWAS640001 (human)) Homo sapiens

Symbol: GWAS640001_H
Name: alcohol consumption measurement QTL GWAS640001 (human)
RGD ID: 406991025
Trait: alcohol consumption measurement
Measurement Type: ethanol drink intake rate   (CMO:0001407)    
LOD Score: Not Available
P Value: 8.0E-13
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38116,297,583 - 16,297,584RGD_MAPPER_PIPELINEGRCh38
GRCh37116,624,078 - 16,624,079RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS640001_HHumanethanol drink intake rate  IAGPrs4291495405850206Based on the EFO term IDGWAS_CATALOGPMID:36477530

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS640001_HHumanalcohol consumption measurement  IAGPrs4291495405850206 GWAS_CATALOGPMID:36477530
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1312431FBXO42F-box protein 4211624684016352480Human

Position Markers

Peak: (rs4291495)
Human AssemblyChrPosition (strand)Source
GRCh38116,297,583 - 16,297,584RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
406991025GWAS640001_Halcohol consumption measurement QTL GWAS640001 (human)8e-13alcohol consumption measurementethanol drink intake rate (CMO:0001407)11629758316297584Human
406897031GWAS546007_Hsmoking initiation QTL GWAS546007 (human)2e-09smoking initiation11629758316297584Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS546007_H GCST90243968 Smoking initiation 2,669,029 European ancestry individuals T 0.393 2E-9 8.699 rs4291495 0.00533 smoking initiation (EFO:0005670)
 PMID:36477530
GWAS640001_H GCST90243989 Drinks per week 2,965,643 European ancestry, East Asian ancestry, Hispanic or Latin American, African ancestry individuals T 0.4 8E-13 12.097 rs4291495 0.006 alcohol consumption measurement (EFO:0007878)
 PMID:36477530
Database Acc Id Source(s)
GWAS Catalog GCST90243989 GWAS Catalog

RGD Curation Notes
Note Type Note Reference