GWAS620677_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS620677_H (myeloid white cell count QTL GWAS620677 (human)) Homo sapiens

Symbol: GWAS620677_H
Name: myeloid white cell count QTL GWAS620677 (human)
RGD ID: 406971701
Trait: myeloid white cell count
Measurement Type: white blood cell count   (CMO:0000027)    
LOD Score: Not Available
P Value: 1.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3818,853,597 - 8,853,598RGD_MAPPER_PIPELINEGRCh38
GRCh3718,913,656 - 8,913,657RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS620677_HHumanwhite blood cell count  IAGPrs12752838405850206Based on the EFO term IDGWAS_CATALOGPMID:27863252

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS620677_HHumanmyeloid white cell count  IAGPrs12752838405850206 GWAS_CATALOGPMID:27863252
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs12752838)
Human AssemblyChrPosition (strand)Source
GRCh3818,853,597 - 8,853,598RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
406974593GWAS623569_Hneutrophil count QTL GWAS623569 (human)4e-11neutrophil quantity (VT:0000222)blood neutrophil count (CMO:0000030)188535978853598Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
406961541GWAS610517_Hneutrophil count, eosinophil count QTL GWAS610517 (human)3e-11eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)188535978853598Human
406971701GWAS620677_Hmyeloid white cell count QTL GWAS620677 (human)1e-10myeloid white cell countwhite blood cell count (CMO:0000027)188535978853598Human
406977256GWAS626232_Hneutrophil count, basophil count QTL GWAS626232 (human)2e-11basophil quantity (VT:0002607)blood basophil count (CMO:0000034)188535978853598Human
406960008GWAS608984_Hgranulocyte count QTL GWAS608984 (human)1e-11granulocyte countblood granulocyte count (CMO:0000111)188535978853598Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS608984_H GCST004614 Granulocyte count 169,822 European ancestry individuals G 0.5035 1E-11 11 rs12752838 0.02429055 granulocyte count (EFO:0007987)
 PMID:27863252
GWAS610517_H GCST004613 Sum neutrophil eosinophil counts 170,384 European ancestry individuals G 0.5035 3E-11 10.523 rs12752838 0.02389095 neutrophil count (EFO:0004833)
eosinophil count (EFO:0004842)
 PMID:27863252
GWAS620677_H GCST004626 Myeloid white cell count 169,219 European ancestry individuals G 0.5034 1E-10 10 rs12752838 0.02328894 myeloid white cell count (EFO:0007988)
 PMID:27863252
GWAS623569_H GCST004629 Neutrophil count 170,702 European ancestry individuals G 0.5035 4E-11 10.398 rs12752838 0.02361786 neutrophil count (EFO:0004833)
 PMID:27863252
GWAS626232_H GCST004620 Sum basophil neutrophil counts 170,143 European ancestry individuals G 0.5035 2E-11 10.699 rs12752838 0.02400847 neutrophil count (EFO:0004833)
basophil count (EFO:0005090)
 PMID:27863252
Database Acc Id Source(s)
GWAS Catalog GCST004626 GWAS Catalog

RGD Curation Notes
Note Type Note Reference