GWAS590060_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS590060_H (BMI-adjusted waist-hip ratio QTL GWAS590060 (human)) Homo sapiens

Symbol: GWAS590060_H
Name: BMI-adjusted waist-hip ratio QTL GWAS590060 (human)
RGD ID: 406941084
Trait: BMI-adjusted waist-hip ratio
LOD Score: Not Available
P Value: 4.0E-18
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3813,056,869 - 3,056,870RGD_MAPPER_PIPELINEGRCh38
GRCh3712,973,433 - 2,973,434RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS590060_HHumanBMI-adjusted waist-hip ratio  IAGPrs2993481405850206 GWAS_CATALOGPMID:31669095
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
151670046LOC124903827translation initiation factor IF-2130554233075562Human

Position Markers

Peak: (rs2993481)
Human AssemblyChrPosition (strand)Source
GRCh3813,056,869 - 3,056,870RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
407201493GWAS850469_Hmonocyte count QTL GWAS850469 (human)4e-13monocyte quantity (VT:0000223)blood monocyte count (CMO:0000032)130568693056870Human
407094945GWAS743921_HBMI-adjusted waist-hip ratio QTL GWAS743921 (human)2e-17BMI-adjusted waist-hip ratio130568693056870Human
407070470GWAS719446_Hwaist-hip ratio QTL GWAS719446 (human)5e-08waist-hip ratiowaist to hip ratio (WHR) (CMO:0000020)130568693056870Human
407361522GWAS1010498_HBMI-adjusted waist-hip ratio QTL GWAS1010498 (human)3e-11BMI-adjusted waist-hip ratio130568693056870Human
407111950GWAS760926_Hwaist-hip ratio QTL GWAS760926 (human)1e-17waist-hip ratiowaist to hip ratio (WHR) (CMO:0000020)130568693056870Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
407350763GWAS999739_HBMI-adjusted waist-hip ratio QTL GWAS999739 (human)5e-11BMI-adjusted waist-hip ratio130568693056870Human
406941084GWAS590060_HBMI-adjusted waist-hip ratio QTL GWAS590060 (human)4e-18BMI-adjusted waist-hip ratio130568693056870Human
407071341GWAS720317_HBMI-adjusted waist-hip ratio QTL GWAS720317 (human)9e-20BMI-adjusted waist-hip ratio130568693056870Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS590060_H GCST009858 Waist-to-hip ratio adjusted for BMI 457,690 European ancestry individuals ? NR 4E-18 17.398 rs2993481 N/A BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:31669095
GWAS719446_H GCST008734 Waist-hip ratio 663,598 European ancestry individuals T 0.19 5E-8 7.302 rs2993481 N/A waist-hip ratio (EFO:0004343)
 PMID:30575882
GWAS720317_H GCST008733 Waist-to-hip ratio adjusted for BMI 660,648 European ancestry individuals T 0.19 9E-20 19.046 rs2993481 0.021 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:30575882
GWAS743921_H GCST008994 Waist-to-hip ratio adjusted for BMI 379,501 European ancestry female individuals A 0.6703 2E-17 16.699 rs2993481 0.0195 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:30239722
GWAS760926_H GCST007067 Waist-hip ratio approximately 458,000 European ancestry individuals ? NR 1E-17 17 rs2993481 N/A waist-hip ratio (EFO:0004343)
 PMID:30595370
GWAS850469_H GCST90002393 Monocyte count 408,112 British individuals T 0.187029 4E-13 12.398 rs2993481 0.020602345 monocyte count (EFO:0005091)
 PMID:32888494
GWAS999739_H GCST90020027 Waist-hip index 219,872 British ancestry women T NR 5E-11 10.302 rs2993481 0.02369 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:34021172
GWAS1010498_H GCST90020025 Waist-to-hip ratio adjusted for BMI 219,872 British ancestry women T NR 3E-11 10.523 rs2993481 0.0239756 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:34021172
Database Acc Id Source(s)
GWAS Catalog GCST009858 GWAS Catalog

RGD Curation Notes
Note Type Note Reference