GWAS568482_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS568482_H (balding measurement QTL GWAS568482 (human)) Homo sapiens

Symbol: GWAS568482_H
Name: balding measurement QTL GWAS568482 (human)
RGD ID: 406919506
Trait: balding measurement
Measurement Type: coat/hair morphological measurement   (CMO:0001807)    
LOD Score: Not Available
P Value: 2.0E-42
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38110,673,022 - 10,673,023RGD_MAPPER_PIPELINEGRCh38
GRCh37110,733,079 - 10,733,080RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS568482_HHumancoat/hair morphological measurement  IAGPrs143353512405850206Based on the EFO term IDGWAS_CATALOGPMID:30573740

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS568482_HHumanbalding measurement  IAGPrs143353512405850206 GWAS_CATALOGPMID:30573740
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1606535CASZ1castor zinc finger 111063660410796646Human
38640458LOC110120648VISTA enhancer hs28911067201310673061Human

Position Markers

Peak: (rs143353512)
Human AssemblyChrPosition (strand)Source
GRCh38110,673,022 - 10,673,023RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
406925760GWAS574736_Hdiastolic blood pressure, systolic blood pressure QTL GWAS574736 (human)6e-09diastolic blood pressure, systolic blood pressuresystolic blood pressure (CMO:0000004)11067302210673023Human
406919506GWAS568482_Hbalding measurement QTL GWAS568482 (human)2e-42balding measurementcoat/hair morphological measurement (CMO:0001807)11067302210673023Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
406904205GWAS553181_Hdiastolic blood pressure, systolic blood pressure QTL GWAS553181 (human)0.000002diastolic blood pressure, systolic blood pressuresystolic blood pressure (CMO:0000004)11067302210673023Human
407076414GWAS725390_Hbalding measurement QTL GWAS725390 (human)6e-25balding measurementcoat/hair morphological measurement (CMO:0001807)11067302210673023Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS553181_H GCST90239828 Blood pressure (pleiotropy model 1 DBP adjusted for estimated causal effects x SBP) 757,601 European ancestry individuals, 318,891 European ancestry, African American or Afro-Caribbean, Native American ancestry, Asian ancestry individuals ? NR 0.000002 5.699 rs143353512 0.2003644 diastolic blood pressure (EFO:0006336)
systolic blood pressure (EFO:0006335)
 PMID:34989438
GWAS568482_H GCST007020 Male-pattern baldness 205,327 European ancestry males A 0.0366354 2E-42 41.699 rs143353512 0.110882 balding measurement (EFO:0007825)
 PMID:30573740
GWAS574736_H GCST90239829 Blood pressure (pleiotropy model 2 SBP adjusted for estimated causal effects x DBP) 757,601 European ancestry individuals, 318,891 European ancestry, African American or Afro-Caribbean, Native American ancestry, Asian ancestry individuals ? NR 6E-9 8.222 rs143353512 0.3724902 diastolic blood pressure (EFO:0006336)
systolic blood pressure (EFO:0006335)
 PMID:34989438
None Available GCST009464 Facial morphology 10,115 European ancestry individuals A NR 6E-9 8.222 rs143353512 0.287 facial morphology measurement (EFO:0007841)
 PMID:31763980
GWAS725390_H GCST007038 Balding type 1 approximately 208,000 European ancestry individuals ? NR 6E-25 24.222 rs143353512 N/A balding measurement (EFO:0007825)
 PMID:30595370
Database Acc Id Source(s)
GWAS Catalog GCST007020 GWAS Catalog

RGD Curation Notes
Note Type Note Reference