GWAS550747_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS550747_H (plasma betaine measurement QTL GWAS550747 (human)) Homo sapiens

Symbol: GWAS550747_H
Name: plasma betaine measurement QTL GWAS550747 (human)
RGD ID: 406901771
Trait: plasma betaine measurement
LOD Score: Not Available
P Value: 7.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38111,829,758 - 11,829,759RGD_MAPPER_PIPELINEGRCh38
GRCh37111,889,815 - 11,889,816RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS550747_HHumanplasma betaine measurement  IAGPrs112521149405850206 GWAS_CATALOGPMID:36357675
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1313372CLCN6chloride voltage-gated channel 611180619111843130Human

Position Markers

Peak: (rs112521149)
Human AssemblyChrPosition (strand)Source
GRCh38111,829,758 - 11,829,759RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
406966737GWAS615713_Hmean corpuscular volume QTL GWAS615713 (human)3e-09mean corpuscular volumemean corpuscular volume (CMO:0000038)11182975811829759Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
406979521GWAS628497_Hlow density lipoprotein cholesterol measurement QTL GWAS628497 (human)4e-08low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)11182975811829759Human
406901771GWAS550747_Hplasma betaine measurement QTL GWAS550747 (human)7e-10plasma betaine measurement11182975811829759Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS550747_H GCST90245124 Betaine levels 14,296 European ancestry individuals A 0.1081 7E-10 9.155 rs112521149 0.10247809 plasma betaine measurement (EFO:0007787)
 PMID:36357675
GWAS615713_H GCST004602 Mean corpuscular volume 172,433 European ancestry individuals A 0.1096 3E-9 8.523 rs112521149 0.03431455 mean corpuscular volume (EFO:0004526)
 PMID:27863252
GWAS628497_H GCST90002412 Low density lipoprotein cholesterol levels 431,167 European ancestry individuals G 0.890774 4E-8 7.398 rs112521149 0.0169696 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:32493714
Database Acc Id Source(s)
GWAS Catalog GCST90245124 GWAS Catalog

RGD Curation Notes
Note Type Note Reference