Gluco32 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Gluco32 (Glucose level QTL 32) Rattus norvegicus

Symbol: Gluco32
Name: Glucose level QTL 32
RGD ID: 2290374
Trait: blood glucose amount   (VT:0000188)    
Measurement Type: blood glucose level area under curve (AUC)   (CMO:0000350)    
LOD Score: 6.27
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2437,177,950 - 44,463,908RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0435,138,860 - 43,414,792RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0434,996,009 - 44,024,417RGDRnor5.0
RGSC_v3.4434,206,019 - 41,729,771RGDRGSC3.4
RGSC_v3.1434,324,560 - 41,849,418RGD
Cross Type: intercross
Strains Crossed: CDR/Ygl CDS/Ygl 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
Ica1 is a candidate Gene for Gluco32

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Measurement Method

Vertebrate Trait

Rat Strain
CDR/Ygl  (IEA)
CDS/Ygl  (IEA)

References

Related QTLs

Related QTL Description Reference
Gluco61 maps to same region RGD:2326163


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
3218Nxph1neurexophilin 143699806837311135Rat
3600Rps4x-ps9ribosomal protein S4, X-linked, pseudogene 943775837337759289Rat
1303037Tmem106btransmembrane protein 106B44132812541347315Rat
71011Gpr85G protein-coupled receptor 8544210013842109584Rat
1307778Tmem168transmembrane protein 16844183062341858763Rat
1309532MdficMyoD family inhibitor domain containing44397231044052162Rat
1560448LOC500028hypothetical protein LOC50002843791783737918511Rat
1561312Ppp1r3aprotein phosphatase 1, regulatory subunit 3A44293735342980195Rat
1565400RGD1565400similar to actin 3 - fruit fly (Drosophila melanogaster) (fragments)43762082037622087Rat
1561223Vwdevon Willebrand factor D and EGF domains44145357341525421Rat
1563764Phf14PHD finger protein 1444000969140195870Rat
1559697Foxp2forkhead box P244313382743712442Rat
1566201Thsd7athrombospondin type 1 domain containing 7A44046112440899345Rat
1584730LOC681013similar to Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22)43976968439770132Rat
1585861LOC680928similar to TGF beta-inducible nuclear protein 143756118837561974Rat
1584719Ndufa4Ndufa4, mitochondrial complex associated44000221640009384Rat
1585845Rbmxl1bRbmx like 1B44395626543957973Rat
1585825LOC680964similar to high mobility group nucleosomal binding domain 143860485638606026Rat
1564521Tas2r7ltaste receptor type 2 member 7-like44156953641570447Rat
1562387RGD1562387similar to GTP-binding protein NGB43939107939425066Rat
1583532LOC681159similar to Glucosamine 6-phosphate N-acetyltransferase (Phosphoglucosamine transacetylase) (Phosphoglucosamine acetylase) (EMeg32 protein)44154887241549774Rat
1564656LOC500035hypothetical protein LOC50003544197006441978344Rat
1588441Bmt2base methyltransferase of 25S rRNA 2 homolog44188163041945472Rat
1587202LOC502730similar to Pyruvate kinase isozymes M1/M2 (Pyruvate kinase muscle isozyme)44115613841277227Rat
1597981LOC681293similar to heterogeneous nuclear ribonucleoprotein A344246088042461983Rat
2322154LOC100360402hypothetical LOC10036040243919157039192321Rat
2322826LOC100363521hypothetical LOC10036352144214169642143340Rat
2322347LOC100360305hypothetical LOC10036030543801322738013802Rat
2323857LOC100359436rCG25051-like44223615742358953Rat
6493676LOC100911252peptidyl-prolyl cis-trans isomerase A-like44182887341829619Rat
7641224LOC102548177uncharacterized LOC10254817744068219240683121Rat
7609534LOC102548489uncharacterized LOC10254848944169446041701116Rat
7596691LOC102547989uncharacterized LOC10254798943959860439678420Rat
7545679LOC102548706LYR motif-containing protein 4-like44187003941878699Rat
9330178LOC10369207460 kDa heat shock protein, mitochondrial pseudogene44072136940732042Rat
11363596LOC108350856uncharacterized LOC10835085644093701340945223Rat
11516558LOC10835085540S ribosomal protein S23 pseudogene43826319438263628Rat
41140158LOC120102687small nucleolar RNA SNORA1744030905740309173Rat
41264909LOC120102634small nucleolar RNA SNORA4444186943541869561Rat
41122445LOC120102236uncharacterized LOC12010223644016991540171995Rat
41291133LOC120102511uncharacterized LOC12010251144160833041656692Rat
41230048LOC120102706small nucleolar RNA SNORA1744239883242398962Rat
41374934LOC120102237fatty acid-binding protein, heart-like44218552542189209Rat
40971411LOC120102154uncharacterized LOC12010215443864163538646263Rat
41011912LOC120102753U2 spliceosomal RNA44418613544186318Rat
40982246LOC120102694small nucleolar RNA SNORA1743973394139734060Rat
41002968LOC120102235uncharacterized LOC12010223544011938740123944Rat
41248065LOC120102234uncharacterized LOC12010223443890194838907419Rat
41319059LOC120102653small nucleolar RNA SNORA4843748469037484833Rat
41065803LOC120102155uncharacterized LOC12010215544198883241995216Rat
41017590LOC120102597U6 spliceosomal RNA44272163142721733Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
34238D4Mgh225043952426439524530Ratregion
34716D4Mgh1413343950527539505420Ratregion
36037D4Rat1313944199617341996312Ratregion
35625D4Rat1417944446372044463908Ratregion
35847D4Rat1214643846577438465927Ratregion
39688D4Rat21110644019349640193597Ratregion
38628D4Rat13022243865742738657645Ratregion
39194D4Rat11524043717795037178180Ratregion
42158D4Arb2613043950527539505418Ratregion
41202D4Rat15219744078009840780283Ratregion
42691D4Rat22321243884718238847397Ratregion
42691D4Rat22321243884718238847569Ratregion
41888D4Rat28224544086875240869000Ratregion
43782D4Got2017943854696138547140Ratregion
43783D4Got2116643723314237233308Ratregion
43784D4Got15714743773361237733759Ratregion
43786D4Got2423943831722238317461Ratregion
43787D4Got2517643896180238961978Ratregion
43788D4Got2724744246796842468215Ratregion
60436D4Got2629844019331240193610Ratregion
625773D4Got2317343854696938547140Ratregion
67352D4Arb1717443775307137753245Ratregion
1627175D4Uia1043928891439289215Ratregion
1634619D4Got25013944276291542763049Ratregion
5025984RH13045718344405177444051957Ratregion
5031516AU04807115244137361441373766Ratregion
5035282BF38772015244042285340423004Ratregion
5025312RH12783621844214200542142223Ratregion
5054585RH14330929444045571040456004Ratregion
5052935RH14235916844183074041830908Ratregion
5045212RH13104818944404993944050128Ratregion
5042684RH12958221844183065741830875Ratregion
5041326RH12879318244183058041830762Ratregion
5072032RH13542518544134566041345845Ratregion
5077590RH13984420744294128342941489Ratregion
5073408RH13741921244210347342103685Ratregion
5071908RH13535419144015848840158679Ratregion
5061744BF40286713944359936643599506Ratregion
5066604AU04825920244342807743428279Ratregion
5066768AU04816217744094735740947534Ratregion
5068462AU04713019644085057940850773Ratregion
5068546AU04708123944392530943925548Ratregion
5069236AU04663019644199616441996360Ratregion
5061882AW53398816244297937742979539Ratregion
5064052BE12056815144076225440762405Ratregion
5060546BE11030918344371069243710875Ratregion
5064674BF39954820044063049440630695Ratregion
5066388AU04838617244397204843972220Ratregion
5082127AW25190013844187895641879091Ratregion
5084698AI1706789744294041142940508Ratregion
5507437REN10325625144367232243672573Ratregion
5507439REN10328524644367896343679209Ratregion
5507441REN10328625144367917743679428Ratregion
5507443REN10341323444370637243706606Ratregion
5507445REN10341424644370655343706799Ratregion
5507447REN10340825244370523443705486Ratregion
5507449REN10342325044370841543708665Ratregion
5507451REN10342226644370815243708418Ratregion
5507453REN10342522044370887443709094Ratregion
5507455REN10342426044370863843708898Ratregion
5507457REN10342825344370952043709773Ratregion
5507459REN10342725344370929243709545Ratregion
5507461REN10343124944371029043710539Ratregion
5507463REN10343324844371068843710936Ratregion
5507465REN10364425744375707043757327Ratregion
5507467REN10364924144375826343758504Ratregion
5507469REN10365025544375845643758711Ratregion
5507471REN10371124844377273843772986Ratregion
5507473REN10371225144377297043773221Ratregion
5507475REN10401126144382901643829277Ratregion
5507477REN10544323144420869544208926Ratregion
5507481ECD0408080044346120243462003Ratregion
5507485ECD0461276844345295743453725Ratregion
5507493ECD0608672144375721943757940Ratregion
5507497ECD0669371044364569543646405Ratregion
5503766STS_ADH227543762119337621465Ratregion
5506354UniSTS:47894812943762091737621046Ratregion
5506630ECD0020294644367803743678983Ratregion
5506636ECD0036191244368001243680924Ratregion
5506652ECD0129888444367903043679914Ratregion
5506666ECD0285785144370804743708898Ratregion
5506668ECD0361280344345036943451172Ratregion
5507393REN10220126244344959643449858Ratregion
5507405REN10221325644345247943452735Ratregion
5507413REN10223926244345832043458582Ratregion
5507415REN10225625044346192143462171Ratregion
5507417REN10227722944346671443466943Ratregion
5507419REN10227823644346691943467155Ratregion
5499533stSG61151824444370522043705464Ratregion
5499535stSG611519123744370546943706706Ratregion
5499537stSG611520143644370668643708122Ratregion
5499531stSG611494109844367904443680142Ratregion
5499529stSG611484125844366756343668821Ratregion
5500180MT348240144445596244456363Ratregion
5500336GDB:19474862143775860837759229Ratregion
5500340GDB:19474713143775909837759229Ratregion
5501319ECD1552447444432155944322033Ratregion
5501321ECD1582047444414700944147483Ratregion
5501679UniSTS:26567729344182910041829392Ratregion
5501818MARC_13931-13932:1007579490:149044371020443710694Ratregion
5507387REN10186024844339051643390764Ratregion
5507389REN10185626844338968343389951Ratregion
5507391REN10219422544344800643448231Ratregion
5507395REN10220225144344983443450085Ratregion
5507397REN102203044345005743450379Ratregion
5507399REN10220424944345037343450622Ratregion
5507401REN10220830344345127943451582Ratregion
5507403REN10221426444345271243452976Ratregion
5507407REN10221524244345295843453200Ratregion
5507409REN10221825844345359043453848Ratregion
5507411REN10221924444345382943454073Ratregion
5507421REN10258525144352484743525098Ratregion
5507423REN10287525144358848343588734Ratregion
5507425REN10311824244363820543638447Ratregion
5507427REN10315624444364621043646454Ratregion
5507429REN10323824744366816843668415Ratregion
5507431REN10324024944366862143668870Ratregion
5507433REN10326625544367449243674747Ratregion
5507435REN10326524144367425543674496Ratregion
Position Markers

Flank 1: (D4Rat115)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2437,177,950 - 37,178,180 (+)MAPPER
Rnor_6.0435,138,860 - 35,139,089NCBI
Rnor_5.0434,996,009 - 34,996,238UniSTS
RGSC_v3.4434,206,020 - 34,206,249UniSTS
RGSC_v3.4434,206,019 - 34,206,249RGD
RGSC_v3.1434,324,560 - 34,324,789RGD
Celera432,661,853 - 32,662,082UniSTS
RH 3.4 Map4191.8RGD
RH 3.4 Map4191.8UniSTS
RH 2.0 Map4255.1RGD
SHRSP x BN Map419.87RGD
FHH x ACI Map423.1799RGD
Cytogenetic Map4q21UniSTS
Peak: (D4Rat282)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2440,868,752 - 40,869,000 (+)MAPPER
Rnor_6.0439,073,031 - 39,073,276NCBI
Rnor_5.0438,909,114 - 38,909,359UniSTS
RGSC_v3.4438,029,742 - 38,029,988RGD
RGSC_v3.4438,029,743 - 38,029,988UniSTS
RGSC_v3.1438,148,282 - 38,148,528RGD
Celera436,254,630 - 36,254,875UniSTS
FHH x ACI Map423.1799RGD
FHH x ACI Map423.1799UniSTS
Cytogenetic Map4q21UniSTS
Flank 2: (D4Rat14)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2444,463,720 - 44,463,908 (+)MAPPER
Rnor_6.0443,414,605 - 43,414,792NCBI
Rnor_5.0444,024,230 - 44,024,417UniSTS
RGSC_v3.4441,729,583 - 41,729,771RGD
RGSC_v3.4441,729,584 - 41,729,771UniSTS
RGSC_v3.1441,849,231 - 41,849,418RGD
Celera439,774,296 - 39,774,481UniSTS
RH 3.4 Map4268.2UniSTS
RH 3.4 Map4268.2RGD
RH 2.0 Map4326.6RGD
SHRSP x BN Map427.24RGD
FHH x ACI Map427.69RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61415Eae11Experimental allergic encephalomyelitis QTL 112.9nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)4139505420Rat
634323Hc2Hypercalciuria QTL 22.15urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)421079645210796Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829465958103Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat
631209Bw2Body weight QTL24.2retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)4994088544463908Rat
1300141Bp178Blood pressure QTL 178arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)41002490139524530Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41008408955084089Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41008408955084089Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41008408955084089Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41008408955084089Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41467806559678065Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41793350862933508Rat
70222Eae2Experimental allergic encephalomyelitis QTL 24.3nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)42133334339505420Rat
1354665Stl10Serum triglyceride level QTL 103.57blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)42133334344463908Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)42133334362278020Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42690728575585128Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)42690728575585128Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)42949419581006281Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat
11530004Niddm71Non-insulin dependent diabetes mellitus QTL 710.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)43258419952754138Rat
8655949Rf62Renal function QTL 6222blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)43443011944463908Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)43443048482490359Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)436303261103194984Rat
4889511Gluco61Glucose level QTL 614.70.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)43717795040869000Rat
2290374Gluco32Glucose level QTL 326.27blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)43717795044463908Rat
1300156Bp179Blood pressure QTL 1792.85arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)43846577439524530Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
61475Aia2Adjuvant induced arthritis QTL 25.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)43950527573892441Rat
1331807Rf31Renal function QTL 312.988urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)43952426474726312Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44043338885433388Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44043341485433414Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44345797688457976Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general significant cosegregation for blood glucose level was observed 1626640
qtl_general the SS allele from CDS was responsible for the phenotypes mentioned 1626640
qtl_general measurement method: rats were fasted overnight and then OGTT was performed 1626640
qtl_general software package used: one-way ANOVA and MultiQTL version 2.5 1626640
qtl_general number of animals used: 101 F2 males 1626640
qtl_map this region incorporates 23 known genes and spans 4.9 cM 1626640